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General

BioMed Central, the world’s largest publisher of open access scientific journals, and the Howard Hughes Medical Institute (HHMI) today announced a membership agreement under which HHMI will pay the article processing charges for all research published by HHMI investigators in BioMed Central journals. Articles published under this agreement will be made immediately and freely available on the web in their final published form, and will be deposited in international archives including PubMed Central (PMC). The agreement between HHMI and BioMed Central takes effect for articles submitted after September 1, 2007.

Microbiology

Scientists today reported new evidence that infection with a common virus may be a contributing factor to the obesity epidemic sweeping through the United States and other countries. In laboratory experiments they showed that infection with human adenovirus-36 (Ad-36), long recognized as a cause of respiratory and eye infections in humans, transforms adult stem cells obtained from fat tissue into fat cells. Stem cells not exposed to the virus, in contrast, were unchanged.

Biology

When a cat steps over an obstacle with its front legs, how do its hind legs know what to do" A new study in the August 21st issue of Current Biology, a publication of Cell Press, reveals that it is the foreleg stepping movement itself that leaves a lasting impression. By comparison, feline memories of having just seen an obstacle proved rather fleeting.

Bioinformatics

Research led by the University Warwick into the genomes of two bacteria could save orchards from a previously almost incurable disease and also assist in treating complications arising from human blood transfusions.

Health & Medicine

The U.S. Food and Drug Administration (FDA) has approved Reclast® (zoledronic acid) Injection, the first and only once-yearly treatment for postmenopausal osteoporosis. Approximately 8 million women in the United States suffer from osteoporosis, a disease characterized by low bone mass and reduced bone strength that causes bones to break easily. Osteoporotic fractures are associated with increased morbidity, mortality and healthcare costs.

Biotechnology

Carnegie Mellon University scientists have developed tiny, spherical nanogels that uniformly release encapsulated carbohydrate-based drugs. The scientists created the nanogels using atom transfer radical polymerization (ATRP), which will ultimately enable the nanogels to deliver more drug directly to the target and to dispense the drug in a time-release manner.

Molecular & Cell Biology

The majority of cells in the human brain are not nerve cells but star-shaped glia cells, the so called “astroglia”. “Glia means “glue”, explains Götz. “As befits their name, until now these cells have been regarded merely as a kind of “putty” keeping the nerve cells together.

Health & Medicine

A patient’s expectations about the side effects of chemotherapy usually focus on nausea, hair loss, fatigue and other side effects. Worries about severe allergic reactions to their therapy is usually not a concern.

AIDS & HIV

The media’s message is clear: the AIDS epidemic will be the downfall of families in Africa. A new study by a University of Missouri-Columbia researcher calls that an overstatement. Her study shows that AIDS compounds the issue of poverty in households where poverty is already a prevailing issue, especially when a household loses its primary income earner to AIDS.




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