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Category: Health & Medicine


People abuse #Imodium as an opiate substitute. It is dangerous and potentially deadly. Annals of Emergency Medicine.
WASHINGTON --T he over-the-counter anti-diarrhea medication Imodium®, or its key ingredient loperamide, is increasingly being abused by people attempting to self-treat their opioid addiction, with sometime fatal results. Two case studies outlining the phenomenon were published online Friday in Annals of Emergency Medicine ("Loperamide Abuse Associated with Cardiac Dysrhythmia and Death").

Full articleMay 3, 2016 05:58 PM896 views
Category: Biology

In December 2015 an international group of scientists convened in Austria to discuss the imminent extinction of the northern white rhinoceros and the possibility of bringing the species back from brink of extinction. The discussions of this historic meeting appear in the international Journal Zoo Biology. The publication of this work is designed as part of the ongoing effort to raise awareness for the extinction crisis facing rhinos and many other species while also reaching out to the scientific community to share and gather information.

Full articleMay 3, 2016 05:58 PM664 views
Category: Molecular & Cell Biology

RNA polymerase II (Pol II), a key enzyme in our gene expression, is responsible for transcribing DNA into messenger RNA. Errors in transcription can cause deleterious effect upon repeated translation of erroneous mRNA into protein. Transcription infidelity may result in aging and human diseases such as cancer. During transcription, Pol II can detect the mis-incorporated RNA and backtrack to correct errors to ensure that each messenger RNA created will match with template DNA. However, it remains largely a mystery how Pol II controls the fidelity of gene transcription.

Full articleMay 3, 2016 05:58 PM637 views
Category: Health & Medicine

Autism and cancer share more than 40 risk genes, suggesting that common mechanisms underlying the functions of some of these genes could conceivably be leveraged to develop therapies not just for cancer but for autism as well, an extensive assessment by researchers with the UC Davis MIND Institute and Comprehensive Cancer Center has found.

Full articleMay 3, 2016 05:58 PM562 views
Category: Microbiology


These are microscope images showing two species of algae which swim using tiny appendages known as flagella.
Long before there were fish swimming in the oceans, tiny microorganisms were using long slender appendages called cilia and flagella to navigate their watery habitats. Now, new research reveals that species of single-celled algae coordinate their flagella to achieve a remarkable diversity of swimming gaits.

Full articleMay 3, 2016 05:58 PM425 views
Category: Molecular & Cell Biology

A microscope about the size of a penny is giving scientists a new window into the everyday activity of cells within the spinal cord. The innovative technology revealed that astrocytes--cells in the nervous system that do not conduct electrical signals and were traditionally viewed as merely supportive--unexpectedly react to intense sensation.

Full articleApril 28, 2016 04:59 PM1813 views
Category: Gene Therapy

Pioneering gene therapy has restored some vision to patients with a rare form of genetic blindness for as long as four years, raising hopes it could be used to cure common causes of vision loss, new University of Oxford research published today shows.

Full articleApril 28, 2016 04:59 PM1887 views
Category: Biology


Sleeping bearded dragon (Pogona vitticeps).
Behavioural sleep is ubiquitous among animals, from insects to man. In humans, sleep is also characterized by brain activity: periods of slow-wave activity are each followed by short phases of Rapid-Eye-Movement sleep (REM sleep). These electrical features of brain sleep, whose functions are not well understood, have so far been described only in mammals and birds, but not in reptiles, amphibians or fish. Yet, birds are reptiles--they are the feathered descendants of the now extinct dinosaurs. How then did brain sleep evolve? Gilles Laurent and members of his laboratory at the Max Planck Institute for Brain Research in Frankfurt, Germany, describe for the first time REM and slow-wave sleep in a reptile, the Australian dragon Pogona vitticeps. This suggests that brain sleep dates back at least to the evolution of the amniotes, that is, to the beginning of the colonization of terrestrial landmass by vertebrate animals.

Full articleApril 28, 2016 04:59 PM1428 views
Category: Health & Medicine


Optical microscopy showing ooscysts of Cryptosporidium sp (in red).
An outbreak of an intestinal parasite common in the tropics, known as Cryptosporidium, has been identified for the first time in the Arctic. The discovery was made in Nunavik, Quebec, by a team from the Research Institute of the McGill University Health Centre (RI-MUHC), in collaboration with the Nunavik Department of Public Health, Institut National de Santé Publique du Québec and Health Canada. The discovery, which was documented in the journal PLoS Neglected Tropical Diseases, could have long-term implications for the health of children in Nunavik and Nunavut's communities.

Full articleApril 28, 2016 04:59 PM1318 views
Category: Health & Medicine


Researcher Juan Carlos Saiz from the Department of Biotechnology of the Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria in Madrid studying the Zika virus.
The constant emergence of viral outbreaks has become a permanent threat to human health. Last year, Zika virus infected thousands of people in the Americas. It is also associated to several cases of neurological disorders and has raised worldwide public health alerts. Now due to the urgency, researchers are detailing the characteristics of the virus to find solutions.

Full articleApril 27, 2016 04:45 PM1676 views
Category: Biology


A juvenile lace coral (Pocillopora damicornis), with coral tissue and algal symbionts (brown dots within the tissue) covering the newly grown skeleton.
In a study published today, researchers from the University of Hawai'i at Mānoa (UHM), Rutgers University, and the University of Haifa identified key and novel components of the molecular "toolkit" that allow corals to build their skeletons (called biomineralization) and described when -- in the transformation from floating larvae to coral skeleton -- these components are used.

Full articleApril 27, 2016 04:45 PM1272 views
Category: Biology

Scientists have been studying how visual space is mapped in the cerebral cortex for many decades under the assumption that the map is equal for lights and darks. Surprisingly, recent work demonstrates that visual brain maps are dark-centric and that, just as stars rotate around black holes in the Universe, lights rotate around darks in the brain representation of visual space. The work was done by Jens Kremkow and collaborators in the laboratories of Jose Manuel Alonso at the State University of New York College of Optometry and will be published in the May 5, 2016 issue of Nature (advance online publication and press embargo lifted on April 27, 2016 at 1800 London time / 1300 US Eastern Time). A similar result will be reported in the same issue of Nature by Kuo-Sheng Lee et al. in the laboratories of David Fitzpatrick at the Max Planck Florida Institute for Neuroscience.

Full articleApril 27, 2016 04:45 PM1166 views
Category: Health & Medicine

An international team of including the Lomonosov Moscow State University researchers discovered which enzyme enables Escherichia coli bacterium (E. coli) to breathe. The study is published in the Scientific Reports.

Full articleApril 25, 2016 05:00 PM1820 views
Category: Microbiology

A group of researchers from Osaka University, Hosei University, and Nagoya University have revealed the molecular mechanism that Vibrio cholerae, the etiological agent of cholera, is attracted by bile. This group has also successfully detected the ligand binding to the bacteria chemoreceptor in vivo for the first time. These results may significantly advance research on mechanism and control of V. cholerae.

Full articleApril 25, 2016 05:00 PM1279 views

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