Young women who have cancer treatment often lose their fertility because chemotherapy and radiation can damage or kill their immature ovarian eggs, called oocytes. Now, Northwestern Medicine® scientists have found the molecular pathway that can prevent the death of immature ovarian eggs due to chemotherapy, potentially preserving fertility and endocrine function.

Ocean acidification due to rising carbon dioxide levels will reduce the density of coral skeletons, making coral reefs more vulnerable to disruption and erosion, according to a new study of corals growing where submarine springs naturally lower the pH of seawater.

Discovery of a mutant gene responsible for a disease is a milestone, but for most conditions, it may be only a first step towards a treatment or cure. Understanding Rett Syndrome, an autism spectrum disorder, is further complicated by the fact that the implicated gene controls a suite of other genes. Two papers, published in today's Nature Neuroscience and Nature, reveal key steps in how mutations in the gene for methyl CpG-binding protein (MECP2) cause the condition. The Rett Syndrome Research Trust (RSRT) funded this work with generous support from partners Rett Syndrome Research Trust UK and Rett Syndrome Research & Treatment Foundation.

This photo shows the brick-and-mortar pattern of simulated bone and nacre against the backdrop of real nacre found in the inner shell of many molluscs. Researchers working to design new materials that are durable, lightweight and environmentally sustainable are increasingly looking to natural composites, such as bone, for inspiration: Bone is strong and tough because its two constituent materials, soft collagen protein and stiff hydroxyapatite mineral, are arranged in complex hierarchical patterns that change at every scale of the composite, from the micro up to the macro.

Slowdowns in the transport and delivery of nutrients, proteins and signaling molecules within nerve cells may contribute to the development of the neurodegenerative disorder ALS, according to researchers at the University of Illinois at Chicago College of Medicine.

The teeth of a kangaroo and other extinct marsupials reveal that southeastern Queensland 2.5-5-million-years ago was a mosaic of tropical forests, wetlands and grasslands and much less arid than previously thought. The chemical analysis of tooth enamel that suggests this diverse prehistoric habitat is published June 12 in the open access journal PLOS ONE by Shaena Montanari from the American Museum of Natural History and colleagues from other institutions.

Singing siblings: zebra finches that grew up without their dads and therefore without a "song model ", don't have to worry about a lack of singing repertoire. The song of songbirds is usually transmitted from one generation to the next by imitation learning and is thought to be similar to the acquisition of human speech. Although song is often learnt from an adult model, there is some evidence of active vocal learning among siblings. Researchers from the Max Planck Institute for Ornithology in Seewiesen now showed that juvenile zebra finches that have been raised without their fathers are able to learn their song via a brother that for a short period had been exposed to the father's' song.

This is an artist's illustration of how Archaeopteryx may have looked sporting its new pigmentation. The first complete chemical analysis of feathers from Archaeopteryx, a famous fossil linking dinosaurs and birds, reveals that the feathers were patterned—light in color, with a dark edge and tip—rather than all black, as previously thought.

Hours spent at the video gaming console not only train a player's hands to work the buttons on the controller, they probably also train the brain to make better and faster use of visual input, according to Duke University researchers.

This is a scanning electron micrograph of Sulfolobus solfataricus cells infected with STIV, showing pyramid-like structures on the surface of the cell. Biologists from Indiana University and Montana State University have discovered a striking connection between viruses such as HIV and Ebola and viruses that infect organisms called archaea that grow in volcanic hot springs. Despite the huge difference in environments and a 2 billion year evolutionary time span between archaea and humans, the viruses hijack the same set of proteins to break out of infected cells.

The genome is full of sequence repetitions. Sequence motif is added after sequence motif, sometimes more than a hundred times. Erratically it seems. And these sequence motifs bind proteins that control transcription factors in regions of the genome where no transcription should occur. A conundrum.

This is an artist's illustration of the skeleton of Archicebus achilles. The darkened bones represent the known bony elements of the skeleton found in China. An international team of paleontologists that includes Northern Illinois University anthropologist Dan Gebo is announcing the discovery of a nearly complete, articulated skeleton of a new tiny, tree-dwelling primate dating back 55 million years.

A new study provides surprising evidence that people with narcolepsy have an increased number of neurons that produce histamine, suggesting that histamine signaling may be a novel therapeutic target for this potentially disabling sleep disorder.

This is Christian Derntl in the bio-lab. Lignocellulosic waste such as sawdust or straw can be used to produce biofuel – but only if the long cellulose and xylan chains can be successfully broken down into smaller sugar molecules. To do this, fungi are used which, by means of a specific chemical signal, can be made to produce the necessary enzymes. Because this procedure is, however, very expensive, Vienna University of Technology has been investigating the molecular switch that regulates enzyme production in the fungus. As a result, it is now possible to manufacture genetically modified fungi that produce the necessary enzymes fully independently, thus making biofuel production significantly cheaper.