It is based on detecting short, repetitive DNA segments in the genome of bacteria. Every single bacterial strain has such characteristic repeats. "With this method we are able to identify bacterial strains as well as clarify their genetic relationships. Furthermore, we can show how new pathogenic variants develop," says Manfred Höfle, researcher at the HZI. The results have now been published in the current issue of the scientific journal "Applied and Environmental Microbiology". The work is part of the two European Union funded projects "Healthy Water" and "AQUA-chip". Manfred Höfle is coordinator of both projects that deal with various aspects of the microbiological safety of both, drinking water and sea water.

Daily sex (or ejaculating daily) for seven days improves men's sperm quality by reducing the amount of DNA damage, according to an Australian study presented today (Tuesday) to the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amsterdam.

Scientists from Texas are batty over a new discovery which could lead to the single most important medical breakthrough in human history—significantly longer lifespans. The discovery, featured on the cover of the July 2009 print issue of The FASEB Journal (http://www.fasebj.org), shows that proper protein folding over time in long-lived bats explains why they live significantly longer than other mammals of comparable size, such as mice.

In the past, even modern technologies have failed to produce high-resolution fluorescence images from this depth because of the strong scattering of light. In the Nature Photonics journal, the Munich researchers describe how they can reveal genetic expression within live fly larvae and fish by "listening to light". In the future this technology may facilitate the examination of tumors or coronary vessels in humans.

A new report issued by the International Osteoporosis Foundation (IOF) and published in the scientific journal Osteoporosis International¹, shows that populations across the globe are suffering from the impact of low levels of vitamin D. The problem is widespread and on the increase, with potentially severe repercussions for overall health and fracture rates.

Many species of animals go through a period of torpor to conserve energy when resources are scarce. But when it comes to switching to energy-saving mode, the champion by far among vertebrates is the burrowing frog (Cyclorana alboguttata), which can survive for several years buried in the mud in the absence of any food or water. How do they accomplish this feat? A team of scientists at the University of Queensland have discovered that the metabolism of their cells changes radically during the dormancy period allowing the frogs to maximise the use of their limited energy resources without ever running on empty. This discovery could prove to have important medical applications in the long term. "It could potentially be useful in the treatment of energy-related disorders such as obesity", explains Ms. Sara Kayes who will present her findings at the Society of Experimental Biology Annual Meeting in Glasgow on Monday 29th June 2009.

Between the 1932 and 2008 Olympic Games, world record times of the men's 100m sprint improved by 0.6 seconds due to improved training techniques and technological advances. Imagine if this improvement could be achieved by a simple change in diet. Scientists at the Research Institute of Wildlife Ecology in Austria have managed to achieve an equivalent feat in mice fed on a diet high in polyunsaturated fatty acids.

Playboy founder Hugh Hefner's legacy will live on with a new University of Central Florida study aimed at saving the endangered bunnies named after him.

It has been known for a long time that T cells can attack the body's own structures and, if they infiltrate the CNS, cause diseases such as multiple sclerosis (MS). The T cells damage the myelin sheath, the material that surrounds and protects the fibers of nerve cells. This damage slows down or blocks messages between the brain and the body, leading to various symptoms of MS such as impaired movements.

Scientists at UC Santa Barbara have zeroed in on the genes responsible for changing flower color, an area of research that began with Gregor Mendel's studies of the garden pea in the 1850's.

A new technique for transplanting the ovaries of women who have lost their fertility as a result of cancer treatment was outlined to the 25th annual conference of the European Society of Human Reproduction and Embryology today (Monday 29 June). Dr. Pascal Piver, manager of the IVF Centre at Limoges University Hospital, Limoges, France, described a new, two-step method of ovarian transplant that has produced excellent results in women whose ovaries have been frozen because of cancer treatment. He said that his team's technique worked to restore ovarian function quickly and already one patient from his clinic had had a baby and another had become pregnant.

In a study published online by the Journal of Substance Abuse Treatment, UC Davis researchers report that it takes at least a year for former methamphetamine users to regain impulse control. The results tell recovering substance abusers, their families and drug-treatment specialists that it can take an extended period of time for the brain functions critical to recovery to improve.

Pig heart valves used to replace defective aortic valves in human patients failed much earlier and more often than expected, says a report from cardiac surgeons at Washington University School of Medicine in St. Louis. This is the first report to demonstrate this potential problem, the researchers say.

The thought of coral reefs tends to conjure up images of tropical vacations, complete with snorkeling among tropical fish in crystal clear waters.

People smell them, thump them and eyeball their shape. But ultimately, it's sweetness and a sense of healthy eating that lands a melon in a shopper's cart.

Research from Canada's own Centre for Addiction and Mental Health (CAMH) featured in this week's edition of the Lancet shows that worldwide, 1 in 25 deaths are directly attributable to alcohol consumption. This rise since 2000 is mainly due to increases in the number of women drinking.

Two new construction manuals are now available for the world's smallest lamps. Based on these protocols, scientists from the Max Planck Institute of Colloids and Interfaces have tailor-made nanoparticles that can be used as position lights on cell proteins and, possibly in the future as well, as light sources for display screens or for optical information technology. The researchers produced cadmium sulphide particles in microscopically small membrane bubbles. Depending on which of the construction manuals they follow, the particles can be 4 or 50 nanometres in size. Because the membrane bubbles have the same size as living cells, the scientists' work also provides an indication as to how nanostructures could arise in nature. (Small, published online: June 8, 2009/DOI: 10.1002/smll.200900560)

Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, came a step closer to understanding how cells close gaps not only during embryonic development but also duringwound healing. Their study, published this week in the journal Cell, uncovers a fundamental misconception in the previous explanation for a developmental process called dorsal closure.

Researchers at The University of Texas M. D. Anderson Cancer Center have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer cells.

The goal of DNA barcoding is to find a simple, cheap, and rapid DNA assay that can be converted to a readily accessible technical skill that bypasses the need to rely on highly trained taxonomic specialists for identifications of the world's biota. This is driven by a desire to open taxonomic identifications to all user groups and by the short supply of taxonomists that do not even exist in many groups. Although DNA barcoding is being rapidly accepted in the scientific literature and popular press, some scientists warn that we are being too hasty in wholeheartedly embracing this technique. Dr. David Spooner, a researcher with the USDA and an expert in the potato and tomato family (Solanaceae), offers just such a cautionary note against accepting this technique without closer examination in his recent article, "DNA Barcoding will Frequently Fail in Complicated Groups: An example in Wild Potatoes" in the June 2009 issue of the American Journal of Botany.

Veritide Ltd., a developer of innovative biological identification and detection solutions, today reported that new independent data to be presented at the Biodetection Technologies 2009 conference confirm the exceptional accuracy of its Ceeker™ (pronounced "seeker") portable bacterial detection device in discriminating between anthrax spores and similar-looking hoax substances. The data show that in over two weeks of testing at the Midwest Research Institute in Florida, the company's Ceeker scanner accurately identified 100% of the anthrax samples used and was correct in 95% of tests involving hoax substances. These test results are consistent with similar results produced last year by a New Zealand forensic testing agency, Environmental Science and Research (ESR).

Humans' ability to easily distinguish among many faces and recognize people they know goes way, way back, say researchers reporting online on June 25th in Current Biology, a Cell Press publication. That assertion stems from new evidence that, like us, rhesus monkeys tell their friends from foes by picking up on the precise layout of facial features.

Using a "neurologger" specially designed to record the brain activity of pigeons in flight, researchers reporting online on June 25th in Current Biology, a Cell Press publication, have gained new insight into what goes through the birds' minds as they fly over familiar terrain. The study is the first to simultaneously record electrical brain activity integrated with large-scale navigational movements of free-flying birds, according to the researchers.

Although every cell in the body carries the genes necessary to function as an antibody-producing B cell, only a small proportion of stem cells mature into those important immune-system cells. James Hagman, PhD, Professor of Immunology at National Jewish Health and his colleagues have identified two "molecular motors" that work in opposing directions to control the development of B cells. They published their findings June 19 in the online version of The Proceedings of the National Academy of Sciences USA.

A UCLA study has discovered that chronic exposure during pregnancy to miniscule levels of carbon monoxide damages the cells of the fetal brain, resulting in permanent impairment. The journal BMC (BioMed Central) Neuroscience published the findings June 22 in its online edition.

Researchers studying the nervous control of nematode mating behavior have produced video footage of a male worm preparing to mate with a hermaphrodite. Writing in the open access journal BMC Biology, Allyson Whittaker and Paul Sternberg from the California Institute of Technology investigated the role of the excitatory neurotransmitter acetylcholine in regulating tail muscles to achieve an exploratory embrace.

How did piranhas — the legendary freshwater fish with the razor bite — get their telltale teeth? Researchers from Argentina, the United States and Venezuela have uncovered the jawbone of a striking transitional fossil that sheds light on this question. Named Megapiranha paranensis, this previously unknown fossil fish bridges the evolutionary gap between flesh-eating piranhas and their plant-eating cousins.

People in very early stages of Alzheimer's disease already have trouble focusing on what is important to remember, a UCLA psychologist and colleagues report.

Contrary to predictions, males of high genetic quality are not very successful when it comes to fertilizing eggs. A new study on seed beetles by Swedish and Danish scientists Göran Arnqvist and Trine Bilde shows that when a female mates with several males, the males of low genetic quality are the most successful in fertilizing eggs. The study is published in this week's issue of Science.

In a landmark technical achievement, investigators in the Vanderbilt Center for Structural Biology have used nuclear magnetic resonance (NMR) methods to determine the structure of the largest membrane-spanning protein to date.

Experiment after experiment confirms that a diet on the brink of starvation expands lifespan in mice and many other species. But the molecular mechanism that links nutrition and survival is still poorly understood. Now, researchers at the Salk Institute for Biological Studies have identified a pivotal role for two enzymes that work together to determine the health benefits of diet restriction.

Mitochondria are the powerhouses of cells. Underneath their smooth surface they harbor an elaborately folded inner membrane. It holds a multitude of bottleneck like invaginations, which expand into elongated cavities (cristae). The narrow shape of the entrance or pore to the cristae ('crista junction') allows separation of the intracristal space and storage of molecules. Cytochrome c, for example, an important signaling protein in programmed cell death (apoptosis), is stored in this compartment. When apoptosis is triggered, the pores enlarge and cytochrome c is released into the cytosol. Thus, understanding of how the pore diameter and the shape of the inner membrane are regulated on a molecular basis is of great relevance to a better understanding of mitochondrial function in general. Recently, in cooperation with other research teams, the group of Prof. Andreas Reichert, who has been appointed as professor for Mitochondrial Biology to the Goethe University within the Cluster of Excellence Macromolecular Complexes in 2007, has identified two proteins linked in an antagonistic manner that are relevant for governing inner membrane structure.

Small whales are disappearing from the world's oceans and waterways as they fall victim to fishing gear, pollution, and habitat loss – compounded by a lack of conservation measures such as those developed for great whales, according to a new WWF report.

Although there is no doubt that hypnosis can impact the mind and behavior, the underlying brain mechanisms are not well understood. Now, new research provides fascinating insight into the specific neural effect of the power of suggestion. The study, published by Cell Press in the June 25 issue of the journal Neuron, uncovers the influence of hypnotic paralysis on brain networks involved in internal representations and self imagery.

Evolutionarily speaking, baboons may be our more distant cousins among primates. But when it comes to our experiences with malaria over the course of time, it seems the stories of our two species have followed very similar plots.

Prostasin, a relatively unknown protease enzyme expressed in most epithelial cells, may play a role in the genesis of colorectal cancer. Researchers writing in the open access journal BMC Cancer have associated a reduction in the expression of inhibitors of the enzyme with malignant cellular behavior.

In addition to providing fundamental insights into the early evolution of the estrogen receptor, research by a team at the University of California, San Diego School of Medicine may lead to a contraceptive for female lampreys – a jawless fish considered an invasive pest species in the Great Lakes region of the United States. This could prove important to the Great Lakes region, where lampreys aggressively consume trout, salmon, sturgeon and other game fish.

The pursuit of happiness characterizes the human condition. But for those suffering from stress, money trouble or chronic illness, a positive outlook on life can be difficult to find. Now, a Tel Aviv University researcher says we should look to our genes.

On June 18, the Canada Foundation for Innovation (CFI) announced the award of $9.16 million for the creation of a national technology platform aimed at mapping the human interactome. This national platform, headed by Dr. Benoit Coulombe from the Institut de recherches cliniques de Montréal (IRCM), will not only provide Canadian researchers with new state-of-the-art equipment in proteomics, functional genomics and bioinformatics, but also bring together integrated infrastructure for deciphering the human interactome an expertise that, until now, has been spread in 12 universities across Canada.

Scientists are warning that a new form of unregulated whaling has emerged along the coastlines of Japan and South Korea, where the commercial sale of whales killed as fisheries "bycatch" is threatening coastal stocks of minke whales and other protected species.