Among stem cell biologists there are few better-known proteins than nestin, whose very presence in an immature cell identifies it as a "stem cell," such as a neural stem cell. As helpful as this is to researchers, until now no one knew which purpose nestin serves in a cell.

Research by the University of Exeter has revealed that ants have a big impact on their local environment as a result of their activity as 'ecosystem engineers' and predators.

The presence of introns in genes requires cells to process "messenger RNA" molecules before synthesizing proteins, a process that is costly and often error-prone. It was long believed that this was simply part of the price organisms paid for the flexibility to create new types of protein but recent work has made it clear that introns themselves have a number of important functions. And so attention is gradually shifting to asking why some organisms have so few introns and others so many.

In the early years of the AIDS epidemic, being infected with the virus that causes the disease was considered a virtual death sentence. But with the development of antiretroviral therapy, many with HIV are now living much longer. In fact, it is estimated that by 2015, about half of all HIV-positive individuals will be older than 50.

ANN ARBOR, Mich. — A new study questions the controversial U.S. Preventative Service Task Force recommendations for breast cancer screening, with data that shows starting at a younger age and screening more frequently will result in more lives saved.

When it comes to breaking down plant matter and converting it to energy, the cow has it all figured out. Its digestive system allows it to eat more than 150 pounds of plant matter every day. Now researchers report that they have found dozens of previously unknown microbial enzymes in the bovine rumen – the cow's primary grass-digestion chamber – that contribute to the breakdown of switchgrass, a renewable biofuel energy source.

Phosphate-free automatic dishwashing detergents — introduced to combat the phosphate-fed algae blooms that foul the nation's lakes and rivers — may be making the fish happy. But they're putting a frown on the faces of some consumers who say the new products leave dishes dirty. That's the topic of the cover story in the current edition of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine.

An innovative genetic strategy for rendering T-cells resistant to HIV infection without affecting their normal growth and activity is described in a paper published in Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The paper is available free online at www.liebertpub.com/hum

To combat last year's Deepwater Horizon oil spill, nearly 800,000 gallons of chemical dispersant were injected directly into the oil and gas flow coming out of the wellhead nearly one mile deep in the Gulf of Mexico. Now, as scientists begin to assess how well the strategy worked at breaking up oil droplets, Woods Hole Oceanographic Institution (WHOI) chemist Elizabeth B. Kujawinski and her colleagues report that a major component of the dispersant itself was contained within an oil-gas-laden plume in the deep ocean and had still not degraded some three months after it was applied.

Young staghorn coral that fluoresce redder are less likely to settle and develop into coral polyps than their greener peers, University of Texas at Austin biologists have discovered.

A workhorse of modern biology is sick, and scientists couldn't be happier.

There is considerable interest in understanding transport and information pathways in living cells. It is crucial for both the transport of, for example, medicine into cells, the regulation of cell life processes and their signalling with their environment. New research in biophysics at the Niels Bohr Institute shows surprisingly that the transport mechanisms do not follow the expected pattern. The results have been published in the scientific journal Physical Review Letters.

Under standard laboratory conditions, the human beta-defensin 1 (hBD-1), a human antibiotic naturally produced in the body, had always shown only little activity against microbes. Nevertheless the human body produces it in remarkable quantities. The solution to the puzzle was the investigation process itself, as the research group led by Dr. Jan Wehkamp at the Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology of the Stuttgart-based Robert Bosch Hospital found out.

New research reveals that a hormone best known for stimulating the production of red blood cells can modulate the immune response. The study, published by Cell Press in the January 27th issue of the journal Immunity, finds that erythropoietin (EPO) has contrasting influences on infectious and inflammatory diseases and may be useful in the design of new therapeutic strategies.

In a new paper published Jan. 21 in the journal Science, a team of researchers led by Microbiology and Immunology professor Blossom Damania, PhD, has shown for the first time that the Kaposi sarcoma virus has a decoy protein that impedes a key molecule involved in the human immune response.

The discovery of an ancient fossil, nicknamed 'Mrs T', has allowed scientists for the first time to sex pterodactyls – flying reptiles that lived alongside dinosaurs between 220-65 million years ago.

Researchers have for the first time mapped the complex choreography used by the immune system's T cells to recognize pathogens while avoiding attacks on the body's own cells.

Do mountain tops act as sky islands for species that live at high elevations? Are plant populations on these mountain tops isolated from one another because the valleys between them act as barriers, or can pollinators act as bridges allowing genes to flow among distant populations?

A team of scientists at The Scripps Research Institute and the University of Virginia has determined the structure of the protein package that delivers the genetic material of the human immunodeficiency virus (HIV) to human cells.

Some amoebae do what many people do. Before they travel, they pack a lunch.

Ebola, a virus that causes deadly hemorrhagic fever in humans, has no known cure or vaccine. But a new study by University of Illinois at Chicago scientists has uncovered a family of small molecules which appear to bind to the virus's outer protein coat and may inhibit its entry into human cells.

Only five species of these so-called 'flea' beetles, out of a global total of 60, had been found to date in New Caledonia, in the western Pacific. A three-year study has now enabled Spanish researchers to discover two new herbivorous beetles – Arsipoda geographica and Arsipoda rostrata. These new beetles hold a secret – they feed on plants that the scientists have still not found on the archipelago.

Sharks are unable to distinguish colors, even though their close relatives rays and chimaeras have some color vision, according to new research by Dr. Nathan Scott Hart and colleagues from the University of Western Australia and the University of Queensland in Australia. Their study shows that although the eyes of sharks function over a wide range of light levels, they only have a single long-wavelength-sensitive cone* type in the retina and therefore are potentially totally color blind. Hart and team's findings are published online in Springer's journal Naturwissenschaften – The Science of Nature.

-With an invention that can be made from some of the same parts used in CD players, University of Michigan researchers have developed a way to measure the growth and drug susceptibility of individual bacterial cells without the use of a microscope.

In birds as in people, female fertility declines with age. But some female birds can slow the ticking of their biological clocks by choosing the right mates, says a new study.

Using chemical compounds found in a Japanese plant as a lead and the clever application of ultraviolet light, a Scripps Research Institute team has created a unique library of dozens of synthetic compounds to test for biomedical potential. Already, one of the compounds has shown great promise in inhibiting replication of HIV particles and fighting inflammation.

A small slice of RNA inhibits prostate cancer metastasis by suppressing a surface protein commonly found on prostate cancer stem cells. A research team led by scientists at The University of Texas MD Anderson Cancer Center reported today in an advance online publication at Nature Medicine.

Travel just one millimeter inside the brain and you'll be stepping into the dark.

Scientists have identified a protein that acts as a "master switch" in certain white blood cells, determining whether they promote or inhibit inflammation. The study, published in the journal Nature Immunology, could help researchers look for new treatments for diseases such as rheumatoid arthritis that involve excessive inflammation.

Chickens genetically modified to prevent them spreading bird flu have been produced by researchers at the Universities of Cambridge and Edinburgh.

Scientists have for the first time sequenced and reconstructed the genomes of most of the microbes in the gut of a premature newborn and documented how the microbe populations changed over time.

Massachusetts General Hospital (MGH) Cancer Center researchers have discovered a previously unknown feature of common tumor cells – massive overexpression of certain DNA sequences that do not code for proteins. These DNA sequences – called satellite repeats – have been studied for their role in chromosomal structure but previously were not suspected of having a role in cancer. The report will appear in the journal Science and is receiving early online release.

A research team from across the United States and Ecuador has pinpointed 1898 as the year the avipoxvirus, or avian pox, hit the Galapagos Islands and started infecting its birds. This estimation is vital to understanding avian diseases that affect today's Galapagos birds. The scientists' paper on the subject, "110 Years of Avipoxvirus on the Galapagos Islands," will be published on January 13 in PLoS ONE, an international, open-access science publication.

The findings show that missing a night of sleep burns roughly 135 calories, the equivalent of two slices of bread or a 225 ml glass of semi-skimmed milk. In terms of physical exertion, this amounts to walking just under two miles. On the flip side, eight hours of sleep saved the same approximate amount of energy.

Scientists from Texas have made an important step toward understanding human mating behavior by showing that certain genes become activated in fruit flies when they interact with the opposite sex. This research, published in the January 2011 issue of the journal GENETICS (http://www.genetics.org), shows that courtship behaviors may be far more influenced by genetics than previously thought. In addition, understanding why and how these genes become activated within social contexts may also lead to insight into disorders such as autism.

A researcher at Albert Einstein College of Medicine of Yeshiva University has helped to develop the first genetic blood test for predicting the chances that in vitro fertilization (IVF) will lead to a successful pregnancy. The test, reported in the online medical journal PLoS One, is based on the finding that different subtypes of the FMR1 gene (also known as the fragile X mental retardation gene) in potential mothers are associated with significantly different chances of conceiving with IVF.

Van Andel Research Institute (VARI) researchers have developed a method that can yield more information from archived newborn blood that has implications for a vast array of research, including population health studies and answering questions about diseases in infants and children.

As H1N1 'Swine Flu' returns to the national headlines a new research paper reveals the key lessons about the origins of the 2009 pandemic. The paper, published today in BioEssays, reveals how the pandemic challenges the traditional understanding of 'antigenic shift' , given that the virus emerged from an existing influenza subtype.

23andMe has released its first annual list of what it felt to be the 10 most interesting and significant genetic findings in 2010, as part of an ongoing journey to understand the role of genetics in personal health and human development.

One of the challenges of gene therapy - a set of methodologies aimed at treating several nucleic acid diseases (DNA or RNA) - is to assure that this material arrives directly to the nucleus of the cell without losing a substantial amount along the way and without producing any undesired side effects. With this aim, scientists experiment with the use of different types of vectors, molecules capable of transporting genetic material to the correct place. Presently, natural "deactivated" viruses are the most commonly used vectors in clinical trials, their side effects however often limit therapeutic application.