Depression is actually defined by specific clinical symptoms such as sadness, difficulty to experience pleasure, sleep problems etc., present for at least two weeks, with impairment of psychosocial functioning. These symptoms guide the physician to make a diagnosis and to select antidepressant treatment such as drugs or psychotherapy.

A tiny marine filter-feeder, that anchors itself to the sea bed, offers new clues to scientists studying the stability of the West Antarctic Ice Sheet – a region that is thought to be vulnerable to collapse(1).

With a simple click of the camera, scientists from the Wildlife Conservation Society and Zoological Society of London have developed a new way to accurately monitor long-term trends in rare and vanishing species over large landscapes.

It now appears that the malaria mosquito needs more than one family of odor sensors to sniff out its human prey.

A team led by Massachusetts General Hospital (MGH) scientists has developed a new microfluidic tool for quickly and accurately isolating neutrophils – the most abundant type of white blood cell – from small blood samples, an accomplishment that could provide information essential to better understanding the immune system's response to traumatic injury. The system, described in a Nature Medicine paper that received advance online release, also can be adapted to isolate almost any type of cell.

The notion that cutting or burning oneself could provide relief from emotional distress is difficult to understand for most people, but it is an experience reported commonly among people who compulsively hurt themselves.

By describing a new double-clawed and highly-unusual relative of Velociraptor, paleontologists have answered a long-standing question: what did the Late Cretaceous predatory dinosaurs in Europe look like? Balaur bondoc, described this week in Proceedings of the National Academy of Sciences, is the first reasonably complete skeleton of a meat-eating dinosaur from the final 60 million years of the Age of Dinosaurs in Europe and provides insight into an ecosystem very different from that of today. Europe at the end of the Cretaceous was awash in higher seas and was an island archipelago dominated by animals smaller and more primitive than their relatives living on larger landmasses.

By comparing two species of ants, Shelley Berger, PhD, the Daniel S. Och University Professor at the University of Pennsylvania, and colleagues Danny Reinberg, PhD, New York University, and Juergen Liebig, PhD, Arizona State University, have established an important new avenue of research for epigenetics -- the study of how the expression or suppression of particular genes affects an organism's characteristics, development, and even behavior.

A team of UK researchers, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), has publicly released the first sequence coverage of the wheat genome. The release is a step towards a fully annotated genome and makes a significant contribution to efforts to support global food security and to increase the competitiveness of UK farming.

One of the most spectacular migrations on Earth is that of the Christmas Island red crab (Gecarcoidea natalis). Acknowledged as one of the wonders of the natural world, every year millions of the crabs simultaneously embark on a five-kilometre breeding migration. Now, scientists have discovered the key to their remarkable athletic feat.

Together with cooperation partners from the U.S., the researchers surrounding Prof. Dr. Martina Havenith (Physical Chemistry II of the RUB) describe their discovery in a so-termed Rapid Communication in the prestigious American chemistry journal, the Journal of the American Chemical Society (JACS). The journal's independent reviewers evaluated the work as one of the top 5% of all submissions.

A new study from researchers in Canada and Sweden has shown that biosynthetic corneas can help regenerate and repair damaged eye tissue and improve vision in humans. The results, from an early phase clinical trial with 10 patients, are published in the August 25th, 2010 issue of Science Translational Medicine.

Functioning much like gears in a machine, cellular motor proteins are critical to dynamic functions throughout the body, including muscle contraction, cell migration and cellular growth processes. Now, neuroscientists from UC Irvine and the Florida campus of The Scripps Research Institute report that motor proteins also play a critical role in the stabilization of long-term memories. The findings add an unexpected dimension to the story of how memories are encoded and suggest new targets for therapeutic interventions.

In the war against infectious disease, identifying the culprit is half the battle. Now, research professor Shaopeng Wang and his colleagues from the Biodesign Institute at Arizona State University, describe a new method for visualizing individual virus particles. Their research opens the door to a more detailed understanding of these minute pathogens, and may further the study of a broad range of micro- and nanoscale phenomena.

How do female whale sharks meet their perfect mates and go on to produce offspring? While little is known about the reproductive behavior of these ocean-roaming giants, a newly published analysis led by University of Illinois at Chicago biologist Jennifer Schmidt reveals new details about the mating habits of this elusive, difficult-to-study fish.

In the aftermath of the explosion of BP's Deepwater Horizon drilling rig in the Gulf of Mexico, a dispersed oil plume was formed at a depth between 3,600 and 4,000 feet and extending some 10 miles out from the wellhead. An intensive study by scientists with the Lawrence Berkeley National Laboratory (Berkeley Lab) found that microbial activity, spearheaded by a new and unclassified species, degrades oil much faster than anticipated. This degradation appears to take place without a significant level of oxygen depletion.

The cave bear started to become extinct in Europe 24,000 years ago, but until now the cause was unknown. An international team of scientists has analysed mitochondrial DNA sequences from 17 new fossil samples, and compared these with the modern brown bear. The results show that the decline of the cave bear started 50,000 years ago, and was caused more by human expansion than by climate change.

More than two and a half billion years ago, Earth differed greatly from our modern environment, specifically in respect to the composition of gases in the atmosphere and the nature of the life forms inhabiting its surface. While today's atmosphere consists of about 21 percent oxygen, the ancient atmosphere contained almost no oxygen. Life was limited to unicellular organisms. The complex eukaryotic life we are familiar with – animals, including humans – was not possible in an environment devoid of oxygen.

In prehistoric times farmers across the world domesticated wild plants to create an agricultural revolution. As a result the ancestral plants have been lost, causing problems for anyone studying the domestication process of modern-day varieties, but that might change. A team led by Fabiola Parra at the Universidad Nacional Autónoma de México (UNAM) has managed to trace a domesticated cactus, the Gray Ghost Organ Pipe (Stenocereus pruinosus) to its living ancestor that can still be found in the Tehuacán Valley in Mexico. The research is published in the September 2010 edition of the Annals of Botany at http://aob.oxfordjournals.org/cgi/content/abstract/106/3/483

A microscopic look into the genes of a Colorado wheat variety has allowed Texas AgriLife Research scientists to identify a wheat streak mosaic virus-resistance gene.

Studies of the spinal fluid of patients given anti-HIV drugs have resulted in new findings suggesting that the brain can act as a hiding place for the HIV virus. Around 10% of patients showed traces of the virus in their spinal fluid but not in their blood – a larger proportion than previously realised, reveals a thesis from the University of Gothenburg, Sweden.

The virus that causes AIDS may undergo changes in the genital tract rendering HIV-1 in semen different than HIV-1 in the blood, according to researchers from the University of North Carolina at Chapel Hill, the Edward Jenner Institute for Vaccine Research (United Kingdom), and the Baylor Pediatric Center of Excellence (Malawi). The research, published August 19 in the open-access journal PLoS Pathogens, advances our understanding of HIV-1 replication in the male genital tract.

U.S. Department of Agriculture (USDA) scientists have developed a new tool for improving the expression of desirable genes in rice in parts of the plant where the results will do the most good.

Scientists at the Smithsonian Institution and the Hawaii Institute of Marine Biology at the University of Hawaii at Manoa have created the first frozen bank for Hawaiian corals in an attempt to protect them from extinction and to preserve their diversity in Hawaii. Mary Hagedorn, an adjunct faculty member at HIMB and a research scientist with the Smithsonian Conservation Biology Institute, leads the laboratory at the HIMB research facilities on Coconut Island in Kaneohe Bay, Oahu, that is banking the frozen coral cells.

Tricking honey bees into thinking they have traveled long distance to find food alters gene expression in their brains, researchers report this month. Their study, in the journal Genes, Brain and Behavior, is the first to identify distance-responsive genes.

A 48-million-year-old fossilised leaf has revealed the oldest known evidence of a macabre part of nature – parasites taking control of their hosts to turn them into zombies.

When we venture out on a cool morning, nothing energises our body like a nice warm drink and new research reveals that bees also use the same idea when they're feeling cold.

The ancient "terror bird" Andalgalornis couldn't fly, but it used its unusually large, rigid skull—coupled with a hawk-like hooked beak—for a fighting strategy reminiscent of boxer Muhammad Ali. The agile creature repeatedly attacked and retreated, landing well-targeted, hatchet-like jabs to take down its prey, according to a new study published this week in the online, open-access journal PLoS ONE by an international team of scientists.

Following up a pioneering 2007 proof-of-concept study, a University of Utah biochemist and colleagues have developed a promising new anti-HIV drug candidate, PIE12-trimer, that prevents HIV from attacking human cells.

Having charted the occurrence of a common chemical change that takes place while stem cells decide their fates and progress from precursor to progeny, a Johns Hopkins-led team of scientists has produced the first-ever epigenetic landscape map for tissue differentiation.

In one of only two studies of its kind, a study from researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts demonstrates that non-viral gene therapy can delay the onset of some forms of eye disease and preserve vision. The team developed nanoparticles to deliver therapeutic genes to the retina and found that treated mice temporarily retained more eyesight than controls. The study, published online in advance of print in Molecular Therapy, brings researchers closer to a non-viral gene therapy treatment for degenerative eye disorders.

The Wildlife Conservation Society today released initial field observations that indicate that a dramatic rise in the surface temperature in Indonesian waters has resulted in a large-scale bleaching event that has devastated coral populations.

Not all viruses are created equal. In liver transplant patients with chronic hepatitis C virus (HCV) infection, only viruses that can dodge the immune response invade the new liver, according to a study published on August 16 in The Journal of Experimental Medicine (www.jem.org).

Maps showing the distribution and prevalence of worm infections in every African country will be launched today (17 August). These maps, called This Wormy World www.thiswormyworld.org, are the first of a series of Global Atlas of Helminth Infections which provide a unique, open-access, free information resource vital for planning and implementing deworming programmes.

Bacteria are well-known to be the cause of some of the most repugnant smells on earth, but now scientists have revealed this lowest of life forms actually has a sense of smell of its own.

Using a new, rapid and less expensive DNA sequencing strategy, scientists have discovered genetic alterations that account for most cases of Kabuki syndrome, a rare disorder that causes multiple birth defects and mental retardation. Instead of sequencing the entire human genome, the new approach sequences just the exome, the 1-2 percent of the human genome that contains protein-coding genes.

HOUSTON - A team of investigators led by a physician-scientist at The University of Texas MD Anderson Cancer Center has shown for the first time that the small protein SUMO can team up with the replication protein A (RPA) complex to facilitate DNA repair. The study is published in the Aug. 13 edition of the journal Molecular Cell.

Two Arizona State University researchers conducting zooarchaeological and archaeometric analyses of four fossilized animal bone fragments found by the Dikika Research Project in northeastern Ethiopia – within walking distance of the discovery of the hominin skeleton "Lucy" (Australopithecus afarensis) – confirm that unusual marks on the bones were inflicted by stone tools. Their conclusion weighs in on findings reported in the Aug. 12 journal Nature, that A. afarensis used sharp-edged stones and a strong striking force to cleave flesh and marrow from large-sized animal carcasses some 3.4 million years ago.

Chemists and engineers at Harvard University have fashioned nanowires into a new type of V-shaped transistor small enough to be used for sensitive probing of the interior of cells.

Single neurons in the brain are surprisingly good at distinguishing different sequences of incoming information according to new research by UCL neuroscientists.