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Health & Medicine

With a $2 million grant from the National Institutes of Health (NIH), researchers from Rensselaer Polytechnic Institute are developing a physics-based virtual model that can simulate a patient's breathing in real time. When used in conjunction with existing 3-D models, adding the fourth dimension of time could significantly improve the accuracy and effectiveness of radiation treatment for lung and liver cancers.

Biology

Magnetic resonance imaging is a very effective method for revealing anatomical details of soft tissues. Contrast agents can help to make these images even clearer and allow physiological processes to be followed in real time. Conventional gadolinium complexes currently used as MRI contrast agent cannot reveal anatomic structures. As reported in the journal Angewandte Chemie, Korean researchers led by Jung Hee Lee at Samsung Medical Center and Taeghwan Hyeon at Seoul National University have now developed a new MRI contrast agent using manganese oxide nanoparticles that produces images of the anatomic structures of mouse brain which are as clear as those obtained by histological examination.

Molecular & Cell Biology

Scientists have identified the receptor in cells of the peripheral nervous system that is most responsible for the body's ability to sense cold.

Biology

Brain "pacemakers" that have helped ease symptoms in people with Parkinson's disease and other movement disorders seem to work by drowning out the electrical signals of their diseased brains.

Biology

Mule deer are giving new meaning to watching out for other mothers' kids.

Molecular & Cell Biology

Many insects living in northern climates don't die at the first signs of cold weather. Rather, new research suggests that they use a number of specialized proteins to survive the chilly months.

Microarray

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease typically characterized by the slow but progressive onset of shortness of breath or cough. Most patients live about five years after diagnosis. However, according to a new study being published today in the online journal PLoS ONE, a subset of patients with a specific genetic profile has a much more rapid progression to complete pulmonary failure and death without a lung transplant.

Environment

In the wake of the U.S. government’s watershed decision to propose listing the polar bear as "Threatened" under the Endangered Species Act, the Wildlife Conservation Society (WCS) is launching a bold initiative to save the Earth’s largest terrestrial predator, not by following the bears themselves, but the receding sea ice habitat that may drastically shrink as a result of global warming. In a project named "Warm Waters for Cool Bears," WCS will use both current and historical satellite imagery to predict where sea ice is likely to persist and where subsequent conservation efforts to save the species will be most effective.

Health & Medicine

A common antipsychotic drug used in emergency rooms to treat methamphetamine overdose damages nerve cells in an area of the brain known to regulate movement, a new study shows.

Health & Medicine

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disorder from which most patients die within 5 years after diagnosis. The disease is characterized by the insidious onset of dyspnea or cough and usually evolves slowly.

Biotechnology

Scientists from Institute of Biophysics and Nanosystems Research (IBN), Austrian Academy of Sciences and of Centre for Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, USA report the study of “Tuning Curvature and Stability of Monoolein Bilayers by Designer Lipid-Like Peptide Surfactants” in the May 30th issue of the online, open-access journal PLoS ONE. Their findings not only help us to understand the basic science of how lipid-like peptides interact with lipid molecules, but also may provide new strategies for the encapsulation and the delivery of biological active materials. They detailed their findings in the report on the impact of integrating short surfactant-like designer peptides in lipidic nanostructures.

Microbiology

A new study conducted by researchers from the University of Verona and the Institute G. Gaslini in Genova, Italy, confirms the pivotal role played by Cytomegalovirus infection in the pathogenesis of atherosclerosis.