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AIDS & HIV

New research conducted at the Uniformed Services University of the Health Sciences (USU) suggests that it may be possible to develop a vaccine that protects against the myriad strains of the HIV virus. HIV is extremely variable, so an effective vaccine may need to stimulate the body to produce cross-reactive antibodies that will neutralize multiple viral strains. These results demonstrate that induction of truly broad-spectrum neutralizing antibodies may be an achievable goal. This groundbreaking study titled: “Extensively Cross-Reactive Anti-HIV-1 Neutralizing Antibodies Induced by gp140 Immunization” appears this week in the Early Edition of Proceedings of the National Academy of Sciences http://www.pnas.org/papbyrecent.shtml.

Health & Medicine

The most powerful genetic analysis of the DNA codes of over 40,000 women -- including those with breast cancer as well as those without the disease – has uncovered five common genetic variants that increase an individual’s risk for breast cancer.

Biology

Long before the National Security Agency began eavesdropping on the phone calls of Americans, young song sparrows were listening to and learning the tunes sung by their neighbors.

Biology

Sharks are known to have a keen sense of smell, which in many species is critical for finding food. However, according to new research from Boston University marine biologists, sharks can not use just their noses to locate prey; they also need their skin – specifically a location called the lateral line. The lateral line is an organ used by all fish to detect, with exquisite sensitivity, movement and vibration in the surrounding water. According to the research team, this is similar to how humans can sense air flow with the small hairs on the face. Until now, it had not been demonstrated that the lateral line also aids in the tracking of odor plumes.

AIDS & HIV

University of Toronto researchers have uncovered the basis by which pregnant women protect themselves against malaria and have also discovered how the HIV virus works to counteract this defence. The research could lead to improved vaccines for pregnant women in malaria-ravished regions.

Molecular & Cell Biology

"Nurse cells" play an important role in deciding which developing infection-fighting cells, called T cells, live and which die, according to research funded by the National Science Foundation (NSF) and reported in the June issue of the journal Experimental Biology and Medicine.

Health & Medicine

A noninvasive ultrasound procedure effectively shrinks uterine fibroids and significantly relieves fibroid-related symptoms in women, according to the results of a multicenter clinical trial reported in the June issue of the journal Radiology. Magnetic resonance-guided, focused ultrasound surgery (MRgFUS) allows radiologists to precisely target fibroids without harming healthy surrounding tissue.

Microbiology

Adults who have recovered from the potentially deadly H5N1 strain of avian influenza may hold the key to future treatments for the virus, according to an international team of researchers. In a study published today in the open access journal PLoS Medicine, the researchers have shown how specific antibodies taken from avian flu survivors in Vietnam can be reproduced in the laboratory and prove effective at neutralising the virus in culture vitro and in mice.

AIDS & HIV

HIV treatment can be delivered even in settings of armed conflict, and humanitarian health agencies should not wait until a conflict is over before launching HIV care programs, say a team from Médecins Sans Frontières (MSF) in this week’s PLoS Medicine.

Health & Medicine

Using magnetic resonance imaging (MRI), radiologists can better predict the likelihood of full or partial recovery of patients with acute spinal cord injuries (SCI), according to a study published in the June issue of the journal Radiology.

Health & Medicine

"Virtual autopsy" performed with multidetector computed tomography (MDCT) can aid forensics teams in determining if a person has drowned, according to a study published in the June issue of Radiology.