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Microarray

Agilent Technologies Inc. (NYSE: A) today announced that its breakthrough Human Genome CGH Microarray technology will be used by researchers at Melbourne's Peter MacCallum Cancer Centre in a three-year study designed to better understand mesothelioma, a cancer found in the lining of the chest, the abdominal cavity and around the heart, usually caused by exposure to asbestos.

Biology

Mice lacking a special protein found only in germ-line cells results in infertility in both males and females, according to a new study from researchers at the University of Pennsylvania School of Medicine. Norman Hecht, PhD, Professor of Human Reproduction in Penn's Center for Research in Reproduction and Women's Health, and colleagues say that these investigations point the way to a new type of contraceptive for both men and women. They report their findings in this week's online edition of the Proceedings of the National Academy of Sciences.

Microbiology

Ebola virus reproduction in laboratory-grown cells is severely hampered by enzyme-inhibiting chemicals, and these chemicals deserve further study as possible treatments for Ebola virus infections in humans, report scientists supported in part by the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH).

Biology

Two new 250 million year-old species of large, meat-eating amphibians have been discovered by researchers, including investigators from McGill University. Their findings published in today's issue of Nature, describe the first and oldest amphibious carnivores from the Republic of Niger in West Africa.

Molecular & Cell Biology

University of California, San Diego biologists and their colleagues have discovered that the genetic system controlling the development and repair of insect cuticle--the outer layer of the body surface in insects--also controls these processes in mammalian skin, a finding that could lead to new insights into the healing of wounds and treatment of cancer.

Environment

Accelerating environmental changes have presented humanity with some significant scientific and engineering challenges, according to the new National Science Foundation (NSF) report, Pathways to the Future: Complex Environmental Systems: Synthesis for Earth, Life and Society in the 21st Century.

Molecular & Cell Biology

A Dutch led international team of researchers has unravelled how nature releases the torque built up in DNA at the molecular level. The researchers from Delft University of Technology, the Ecole Normale Supérieure in Paris and the Sloan-Kettering institute in New York published their findings in the 31 March 2005 issue of Nature. An artistic impression of the enzyme at work is featured on the cover of this issue.

Molecular & Cell Biology

Researchers from the Viikki Biocenter, University of Helsinki, show that atomic structures can reveal evolutionary history of viruses in a similar fashion as fossils did for the dinosaurs and reptiles. Their article is published in the April 15 issue of Molecular Cell.

Microbiology

The universe of microbes that lives in your stomach may be nearly as unique as your fingerprint, according to researchers at the Stanford University School of Medicine who have embarked on the early stages of exploring the intestinal ecosystem.

Biology

The biggest mass extinction in Earth history some 251 million years ago was preceded by elevated extinction rates before the main event and was followed by a delayed recovery that lasted for millions of years. New research by two University of Washington scientists suggests that a sharp decline in atmospheric oxygen levels was likely a major reason for both the elevated extinction rates and the very slow recovery.