A study by researchers at Children's Hospital Los Angeles (CHLA), Brigham and Women's Hospital and the California Department of Public Health suggests that all babies with a known mutation for cystic fibrosis (CF) and second mutation called the 5T allele should receive additional screening in order to better predict the risk of developing CF later in life.

Full-term babies receive natural protection from their mothers that helps them fight off dangerous infections. However, babies born prematurely lack protective intestinal bacteria and often are unable to be nursed, causing their infection-fighting capabilities to be underdeveloped. Now, researchers at the University of Missouri School of Medicine have found that a manufactured form of lactoferrin, a naturally occurring protein in breast milk, can help protect premature infants from a type of staph infection.

Scientists at The University of Nottingham have demonstrated for the first time that it is possible to selectively sequence fragments of DNA in real time, greatly reducing the time needed to analyse biological samples.

This is an illustration of SRM peaks and a human face. Reporting in the journal Cell, Senior Research Scientist Dr. Ulrike Kusebauch, of Institute for Systems Biology (ISB), describes the results of a collaboration between scientists at ISB, ETH Zurich and a number of other contributing institutes to develop the Human SRMAtlas, a compendium of proteomic assays for any human protein. The Human SRMAtlas is a compendium of highly specific mass spectrometry assays for the targeted identification and reproducible quantification of any protein in the predicted human proteome, including assays for many spliced variants, non-synonymous mutations and post-translational modifications. Using the technique called selected reaction monitoring, assays were developed with the use of 166,174 well-characterized, chemically synthesized proteotypic peptides. The SRMAtlas resource is freely publicly available at http://www.srmatlas.org and will equally benefit focused, hypothesis-driven and large proteome-scale studies. We expect this resource will significantly advance protein-based experimental biology to understand disease transitions and wellness trajectories because any human protein can now, in principle, be identified and quantified in any sample.

The images above show, from left to right, functioning stem cells, stem cells no longer functioning due to Hutchinson-Gilford Progeria syndrome (HGPS), and stem cells previously not functioning The fountain of youth may reside in an embryonic stem cell gene named Nanog.

Results show that the transfer efficiency of organic carbon from the surface to the deep ocean About the same amount of atmospheric carbon that goes into creating plants on land goes into the bodies of tiny marine plants known as plankton. When these plants die and sink, bacteria feed on their sinking corpses and return their carbon to the seawater. When plankton sink deep enough before being eaten, this carbon is taken out of circulation as a greenhouse gas to remain trapped in the deep ocean for centuries.