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Health & Medicine

A University of Colorado Cancer study published today in the Journal of the American Medical Informatics Association (JAMIA) describes a new tool that interprets the raw data of whole exome tumor sequencing and then matches the cancer's unique genetics to FDA-approved targeted treatments.

Environment


Fishing boats at the harbor in Luderitz, Namibia. The small town is known for its crayfish industry.
New groundbreaking research shows that with improved fishing approaches -- compared to business as usual -- the majority of the world's wild fisheries could be at healthy levels in just 10 years and global fish populations could double by 2050.

Biotechnology


A new study shows that a hollowed-out version of cowpea mosaic virus could be useful in human therapies.
Viruses aren't always bad. In fact, scientists can harness the capabilities of some viruses for good--modifying the viruses to carry drug molecules, for example.

Molecular & Cell Biology

A novel investigation of how enzymatic reactions can direct the motion and organization of microcapsules may point toward a new theory of how protocells - the earliest biological cells - could have organized into colonies and thus, could have ultimately formed larger, differentiated structures.

Microbiology

Bacteria are the most abundant form of life on Earth, and they are capable of living in diverse habitats ranging from the surface of rocks to the insides of our intestines. Over millennia, these adaptable little organisms have evolved a variety of specialized mechanisms to move themselves through their particular environments. In two recent Caltech studies, researchers used a state-of-the-art imaging technique to capture, for the first time, three-dimensional views of this tiny complicated machinery in bacteria.

Molecular & Cell Biology

According to epigenetics -- the study of inheritable changes in gene expression not directly coded in our DNA -- our life experiences may be passed on to our children and our children's children. Studies on survivors of traumatic events have suggested that exposure to stress may indeed have lasting effects on subsequent generations. But how exactly are these genetic "memories" passed on?

Molecular & Cell Biology


Tardigrades have not acquired a significant proportion of their DNA from other organisms, a new study shows.
Tardigrades, also known as moss piglets or water bears, are eight-legged microscopic animals that have long fascinated scientists for their ability to survive extremes of temperature, pressure, lack of oxygen, and even radiation exposure.

Molecular & Cell Biology


Kent Bradford, left, and Alfred Huo, seen here with a flowering lettuce plant, found that lettuce could be prevented from flowering by increasing the expression of a specific microRNA
Like most annuals, lettuce plants live out their lives in quiet, three-act dramas that follow the seasons. Seed dormancy gives way to germination; the young plant emerges and grows; and finally in the climax of flowering, a new generation of seeds is produced. It's remarkably predictable, but the genetics that coordinates these changes with environmental cues has not been well understood.

Molecular & Cell Biology


Space-filling model of Reb1 bound to DNA.
In a study published on 28 March 2016 in the Proceedings of the National Academy of Sciences, researchers at the Medical University of South Carolina (MUSC) and Virginia Commonwealth University have resolved the first protein structure in a family of proteins called transcription terminators. The crystal structure of the protein, called Reb1, provides insight into aging and cancer, according to Deepak Bastia, Ph.D., Endowed Chair for Biomedical Research in the MUSC Department of Biochemistry and Molecular Biology and co-senior author of the study.