An experimental single-stranded oligonucleotide-based drug, MGN1703, comprised only of natural DNA components, stimulates the human immune system to fight infections and attack cancer cells without causing the harmful side effects associated with similar compounds that also contain non-natural DNA components. The design and structural characteristics of MGN1703, which is in clinical testing to treat a variety of cancers, affect its potency and toxicity, as described in an article in Nucleic Acid Therapeutics

Bacteria have traditionally been viewed as solitary organisms that "hang out on their own," says molecular biologist Kevin Griffith of the University of Massachusetts Amherst. However, scientists now realize that in fact, bacteria exhibit social behavior within groups.

This is a central chimpanzee. The number of gorillas and chimpanzees in Central Africa continues to decline due to hunting, habitat loss, and disease, combined with a widespread lack of... The number of gorillas and chimpanzees in Central Africa continues to decline due to hunting, habitat loss, and disease, combined with a widespread lack of law enforcement and corruption in the judicial process, according to the International Union for Conservation of Nature, Wildlife Conservation Society, WWF, and partners in a new conservation plan.

A clearer understanding of the origin recognition complex (ORC) - a protein complex that directs DNA replication - through its crystal structure offers new insight into fundamental mechanisms of DNA replication initiation. This will also provide insight into how ORC may be compromised in a subset of patients with Meier-Gorlin syndrome, a form of dwarfism in humans.