Researchers at the Johns Hopkins Bloomberg School of Public Health have developed new software that greatly improves the speed at which scientists can analyze RNA sequencing data. RNA sequencing is used to compare differences in gene expression to identify those genes that switched on or off when, for instance, a particular disease is present. However, sequencing instruments can produce billions of sequences per day, which can be time-consuming and costly to analyze. The software, known as Myrna, uses "cloud computing," an Internet-based method of sharing computer resources. Faster, cost-effective analysis of gene expression could be a valuable tool in understanding the genetic causes of disease. The findings are published in the current edition of the journal Genome Biology. The Myrna software is available for free download at http://bowtie-bio.sf.net/myrna.

Scientists from the University of California, San Diego School of Medicine have identified dendritic antigen-presenting cells in zebrafish, opening the possibility that the tiny fish could become a new model for studying the complexities of the human immune system.

For 70 years the world has mismanaged the common good of antibiotics. The result is a growing global burden of antibiotic resistance, threatening to take health care back to an era where ordinary infections might once again become fatal.

Mycoplasmas are responsible for a variety of important diseases, including atypical pneumonia in humans and mastitis in cows, sheep and goats, which results in loss of milk production. Mycoplasmal mastitis represents a particular problem in the dairy industry and is thus a subject of intense study. One of the most important mastitis agents in sheep and goats is Mycoplasma agalactiae, which has been under investigation by the group of Renate Rosengarten and Rohini Chopra-Dewasthaly at the Institute of Bacteriology, Mycology and Hygiene at the University of Veterinary Medicine, Vienna (Vetmeduni Vienna).

Genetically closely related skin bacteria that have developed resistance to several different antibiotics and that can cause intractable care-related infections are found and seem to be spreading within and between hospitals in Sweden.

A research team led by Cary Pirone from the Department of Biological Sciences at Florida International University has identified bilirubin in the popular Bird of Paradise plant. The breakthrough study, published in the September 2010 issue of the American Society for Horticultural Science's journal HortScience, provides new insights into color production in this iconic tropical plant.

Elimination of a molecular gatekeeper leads to the development of arthritis in mice, scientists report in a study published in the Journal of Experimental Medicine. The newly discovered gatekeeper is a protein that determines the fate – survival or death – of damaging cells that mistakenly attack the body's own tissues and lead to autoimmune disorders such as arthritis.