Biology

Two species of damselfish may look identical—not to mention drab—to the human eye. But that's because, in comparison to the fish, all of us are essentially colorblind. A new study published online on February 25th in Current Biology, a Cell Press publication, reveals that the fish can easily tell one species from another based entirely on the shape of the ultraviolet (UV) patterns on their faces.

Molecular & Cell Biology

Ever looked carefully at the leaves on a plant and noticed their various sizes and shapes? Why are they different? What controls the size and shape of each individual leaf? Very little is known about the developmental control of leaf size and shape, and understanding the mechanisms behind this is a major issue in plant biology.

Biology

A team from the University of Copenhagen, led by postdoc Luke Holman of the Center for Social Evolution, describes in Proceedings of the Royal Society B, published on the 24 February 2010, that ant queens are much more devious than previously thought.

Bioinformatics

Twenty billion pieces of DNA in 100 small fish have opened the eyes of biologists studying evolution. After combining new technologies, researchers now know many of the genomic regions that allowed an ocean-dwelling fish to adapt to fresh water in several independently evolved populations.

AIDS & HIV

UCLA AIDS Institute researchers successfully removed CCR5 — a cell receptor to which HIV-1 binds for infection but which the human body does not need — from human cells. Individuals who naturally lack the CCR5 receptor have been found to be essentially resistant to HIV.

Health & Medicine

A recent report by the Institute of Medicine (IOM) confirmed that 3.5 to 5.3 million people (1-2 % of the U.S. population) have chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Despite efforts by federal, state and local government agencies to control and prevent these diseases, they remain a serious public health concern. The major factor impeding efforts to control HBV and HCV is lack of knowledge and awareness among health care providers, social service professionals, members of the public, and policy-makers. The full IOM report is now available online and published in Hepatology, a journal of the American Association for the Study of Liver Diseases (AASLD).

Biology
BiologyFebruary 25, 2010 12:36 AM

Baby monitors of the future could translate infant cries, so that parents will know for certain whether their child is sleepy, hungry, needing a change, or in pain. Japanese scientists report details of a statistical computer program that can analyze a baby's crying in the International Journal of Biometrics.

Biology

A paralyzed patient implanted with a brain-computer interface device has allowed scientists to determine the relationship between brain waves and attention.

Stem Cell Research

An international research team led by Columbia University Medical Center successfully used mouse embryonic stem cells to replace diseased retinal cells and restore sight in a mouse model of retinitis pigmentosa. This strategy could potentially become a new treatment for retinitis pigmentosa, a leading cause of blindness that affects approximately one in 3,000 to 4,000 people, or 1.5 million people worldwide. The study appears online ahead of print in the journal Transplantation (March 27, 2010 print issue).

Biology

A team of paleontologists has discovered a new dinosaur species they're calling Abydosaurus, which belongs to the group of gigantic, long-necked, long-tailed, four-legged, plant-eating dinosaurs such as Brachiosaurus.

Bioinformatics

The origins of flowering plants from peas to oak trees are now in clearer focus thanks to the efforts of University of Florida researchers.

Bioinformatics
BioinformaticsFebruary 23, 2010 05:41 PM

For the first time, scientists have sequenced the entire genome of the pea aphid, a notorious horticultural and agricultural pest. The findings reveal the extent of the genetic collaboration of the aphid host with its bacterial symbiont, which may account for some of the extraordinary characteristics of this insect.

Biology

Iron containing short nerve branches in the upper beak of birds may serve as a magnetometer to measure the vector of the Earth magnetic field (intensity and inclination) and not only as a magnetic compass, which shows the direction of the magnetic field lines. Already several years ago, the Frankfurt neurobiologists Dr.Gerta Fleissner and her husband Prof. Dr. Günther Fleissner have discovered these structures in homing pigeons and have, in close cooperation with the experimental physicist Dr. Gerald Falkenberg (DESY Hamburg), characterized the essential iron oxides."After we had shown the system of dendrites with distinct subcellular iron-containing compartments in homing pigeons, immediately the question was posed whether similar dendritic systems may be found in other bird species, too", as Gerta Fleissner, the principal investigator, comments. Meanwhile they could describe similar candidate structures in the beaks of various avian species. X-Ray-fluorescence measurements at DESY demonstrated that the iron oxides within these nervous dendrites are identical. These findings were published few days ago in the high-ranking interdisciplinary online journal PlosOne.

Biotechnology

Ovarian and breast cancer treatments being developed that mix a protein inhibitor and traditional anticancer drugs are showing signs of success, according to a new review for Faculty of 1000 Biology Reports.

Microbiology

MADISON — Genetic interactions between avian H5N1 influenza and human seasonal influenza viruses have the potential to create hybrid strains combining the virulence of bird flu with the pandemic ability of H1N1, according to a new study.

Molecular & Cell Biology

An extremely small RNA molecule created by a University of Colorado at Boulder team can catalyze a key reaction needed to synthesize proteins, the building blocks of life. The findings could be a substantial step toward understanding "the very origin of Earthly life," the lead researcher contends.

Biology

British Columbia, Canada: DNA recovered from ancient caribou bones reveals a possible link between several small unique caribou herds and a massive volcanic eruption that blanketed much of the Alaskan Yukon territory in a thick layer of ash 1,000 years ago, reports research published today in Molecular Ecology.

Health & Medicine

Irvine, Calif. – A new strain of mosquitoes in which females cannot fly may help curb the transmission of dengue fever, according to UC Irvine and British scientists.

Biology

New research from scientists in Liverpool has revealed the relationship between agility and vision in mammals. The study, published today in the Journal of Anatomy, sampled 51 species to compare the relationship between agility and vision between frontal eyed species, such as cats, to lateral-eyed mammals such as rabbits, to establish if the positioning of the eyes resulted in limitations to speed and agility.

Molecular & Cell Biology

Scientists are reporting the first-ever data to show that the enzyme calcineurin is critical in controlling normal development and function of heart cells, and that loss of the protein leads to heart problems and death in genetically modified mice.

Molecular & Cell Biology

Brain researcher Hiroshi Kawabe has discovered the workings of a process that had been completely overlooked until now, and that allows nerve cells in the brain to grow and form complex networks. The study shows that an enzyme which usually controls the destruction of protein components has an unexpected function in nerve cells: it controls the structure of the cytoskeleton and thus ensures that nerve cells can form the tree-like extensions that are necessary for signal transmission in the brain.

Molecular & Cell Biology

An international team of scientists, including two from Arizona State University, have taken a significant step closer to unlocking the secrets of photosynthesis, and possibly to cleaner fuels.

Molecular & Cell Biology

Life's smallest motor, a protein that shuttles cargo within cells and helps cells divide, does so by rocking up and down like a seesaw, according to research conducted by scientists at the U.S. Department of Energy's Lawrence Berkeley National Laboratory and Brandeis University.

Health & Medicine

BIRMINGHAM, Ala - New findings in a study led by the director of the University of Alabama at Birmingham (UAB) Division of Neonatology show that that training birth attendants in essential newborn-care techniques reduced stillbirths by more than 30 percent - and potentially could save as many as 1 million lives worldwide each year.

Environment

A rapid and unprecedented proliferation of oil and gas concessions threatens the megadiverse Peruvian Amazon. The amount of area leased is on track to reach around 70% of the region, threatening biodiversity and indigenous people. This is one of the central conclusions from a pair of researchers from the Institut de Ciència i Tecnologia Ambientals (ICTA) of Universitat Autònoma de Barcelona (UAB), and the Washington DC-based NGO Save America's Forests, who have, for the first time, documented the full history of hydrocarbon activities in the region and made projections about expected levels of activity in the near future.

Molecular & Cell Biology

A signaling protein that is key in orchestrating the body's overall immune response has an important localized role in fighting bacterial infection and inflammation in the intestinal tract, according to a study by UC San Diego School of Medicine investigators, published in the journal Cell Host and Microbe.

Bioinformatics

An international consortium of scientists, including Universitat Autònoma de Barcelona (UAB) researcher Deodoro Oliveira, have sequenced the genome of three species of parasitoid wasps of the genus Nasonia. The research offers new basic information on the genetic mechanisms of evolution. It is also of great importance for the control of agricultural pests and of insect-borne diseases, since parasitoid wasps bite and lay eggs on much larger insects, many of which are the ones to later cause plagues or spread infectious diseases. The research could pave the way for new methods of controlling these plagues and preventing the propagation of diseases.

Molecular & Cell Biology

In the dominoes that make up human cells, researchers at the University of Michigan Comprehensive Cancer Center have traced another step of the process that stops cells from becoming cancerous.

Bioinformatics

Human genomes from Southern African Bushmen and Bantu individuals have been sequenced by a team of scientists seeking a greater understanding of human genetic variation and its effect on human health. The study's findings will be published in the journal Nature on 18 February 2010. The research was completed by scientists from American, African, and Australian research institutions, with support from Penn State University in the United States and from several U.S. companies that market DNA-sequencing instruments.

Bioinformatics

An international team of researchers has created a genome-scale map of 26 different cancers, revealing more than 100 genomic sites where DNA from tumors is either missing or abnormally duplicated compared to normal tissues. The study, the largest of its kind, finds that most of these genetic abnormalities are not unique to one form of cancer, but are shared across multiple cancers. The work appears in the February 18 issue of the journal Nature.

Health & Medicine

A cheap and simple way of making vaccines stable – even at tropical temperatures – has been proven to work by scientists at Oxford University.

Biotechnology

A "metal foam" that has a similar elasticity to bone could mean a new generation of biomedical implants that would avoid bone rejection that often results from more rigid implant materials, such as titanium. Researchers at North Carolina State University have developed the metal foam, which is even lighter than solid aluminum and can be made of 100 percent steel or a combination of steel and aluminum.

Microbiology

Researchers investigating UK samples have found no association between the controversial xenotropic murine leukaemia virus-related virus (XMRV) and chronic fatigue syndrome (CFS). Their study, published in BioMed Central's open access journal Retrovirology, calls into question a potential link described late last year by an American research team.

Molecular & Cell Biology

If subway terminals didn't exist and people had to exit subway stations to switch subway lines, transit time would increase. People also may encounter distractions, such as grabbing a cup of coffee, instead of getting on the other line. Molecules also use "terminals" to save transit time during enzyme-catalyzed processes. Using advanced X-radiation techniques, University of Missouri researchers were able to visualize one of these terminals inside of an enzyme that degrades proline, which is an amino acid that has a central role in metabolism. In humans, proline is important for suppression of cancer, cell death and oxidation. Understanding the structure of this enzyme will help scientists better understand how it functions and develop drugs that may inhibit its catalytic function.

Biotechnology

Building on his Nobel Prize-winning work creating fluorescent proteins that light up the inner workings of cells, a team of researchers led by Howard Hughes Medical Institute investigator Roger Tsien, PhD, professor of pharmacology, chemistry and biochemistry at the University of California, San Diego and the Moores UCSD Cancer Center has developed biological probes that can stick to and light up tumors in mice. The scientists were able to spot and remove more cancerous tissue in mice injected with the fluorescent probes than in those mice without the fluorescent probes, upping survival five-fold. The findings – reported online the week of February 15 in the early edition of the Proceedings of the National Academy of Sciences – are the latest steps in research aimed at helping surgeons see the outlines of cancerous tumors in real time, and promise to open new doors to using molecular tools in the operating room.

Molecular & Cell Biology

Scientists have discovered a molecular pathway that works through the immune system to regenerate damaged kidney tissues and may lead to new therapies for repairing injury in a number of organs systems.

Molecular & Cell Biology

A new study from the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa suggests that stem cells intentionally break their own DNA as a way of regulating tissue development. The study, published in Proceedings of the National Academy of Science (PNAS), could dramatically change how researchers think about tissue development, stem cells and cancer.

Biology

'Free-stall', untied cattle in small herds produce less milk than cows tied to their stalls but have a higher reproductive performance and suffer less teat injuries and metabolic diseases. Researchers writing in BioMed Central's open access journal Acta Veterinaria Scandinavica compared performance and health within the two stall types in response to a ban on the construction of new tie-stalls.

AIDS & HIV

A new international study reported in PLoS Medicine confirms that a single dose of nevirapine (sdNVP) can lead to HIV treatment failure in women who receive the drug to prevent transmission of the AIDS virus to their infants. However, the increased risk of failure could only be detected in women who began full HIV treatment within about a year after receiving sdNVP.

Microbiology

In a new study, Dartmouth researchers describe the structure of a protein called ToxT that controls the virulent nature of Vibrio cholerae, the bacteria that causes cholera. Buried within ToxT, the researchers were surprised to find a fatty acid that appears to inhibit ToxT, which prevents the bacteria from causing cholera. Cholera, which causes acute diarrhea, can be life threatening, and, according to the World Health Organization, cholera remains a serious threat to global health.




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