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Health & Medicine

Two researchers from the University Hospital and the Center for Applied Medical Research (CIMA) from the University of Navarra have published an article in Nature Cancer Reviews, one of the leading scientific journals in the area of cancer studies. The article, written by Ignacio Melero and Sandra Hervas-Stubbs, together with other scientists from the United States and Great Britain, addresses the use of a new pharmaceutical family with practical applications in cancer and chronic viral illnesses.

Health & Medicine

For the first time in humans, scientists have found early indicators of inflammation — potential warning signs — in work-related injuries caused by repetitive motion.

Molecular & Cell Biology


Ice crystals decorated by fluorescent antifreeze proteins.
Antifreeze or “ice structuring” proteins – found in some fish, insects, plants, fungi and bacteria – attach to the surface of ice crystals to inhibit their growth and keep the host organism from freezing to death. Scientists have been puzzled, however, about why some ice structuring proteins, such as those found in the spruce budworm, are more active than others.

Molecular & Cell Biology


Ovarian cancer tissue showing PAX8 stained in black.
A new study suggests that ovarian cancer cells form by hijacking a developmental genetic process normally used to form fallopian tubes. Scientists at the Georgia Institute of Technology and the Ovarian Cancer Institute discovered that the protein, PAX8, is involved in the development of fallopian tubes and is present in ovarian cancer cells, but not in normal ovarian tissue. The discovery not only provides a new target for diagnostic and therapeutic interventions, but also opens new avenues for basic research in ovarian cancer pathology. The research appears in Volume 104, Issue 3 of the journal Gynceologic Oncology.

Biotechnology

Leafy greens and beans aren't the only foods that pack a punch of folate, the vitamin essential for a healthy start to pregnancy.

Biology


Adult male lance-tailed manakin on a branch
Why do some individuals sacrifice their own self-interest to help others? The evolution and maintenance of cooperative behavior is a classic puzzle in evolutionary biology. In some animal societies, cooperation occurs in close-knit family groups and kin selection explains apparently selfless behavior. Not so for the lance-tailed manakin.

Environment

There's a scholarly debate brewing about whether pre-Columbian Amazonian populations settled in large numbers across Amazonia and created the modern forest setting that many conservationists take to be ‘natural.'

Molecular & Cell Biology


The electron tomogram of a complete yeast cell reveals the cellular architecture. It shows plasma membrane, microtubules and light vacuoles (green), nucleus, dark vacuoles and dark vesicles (gold), mitochondria and large dark vesicles (blue) and light vesicles (pink). Credit: Johanna Höög, EMBL Heidelberg
Editor: A high resolution version of the picture is available!

Like our body every cell has a skeleton that provides it with a shape, confers rigidity and protects its fragile inner workings. The cytoskeleton is built of long protein filaments that assemble into networks whose overall architecture and fine detail can only be revealed with high resolution electron microscopy images. Researchers at the European Molecular Biology Laboratory (EMBL) and the University of Colorado have now obtained the first 3D visualization of a complete eukaryotic cell at a resolution high enough to resolve the cytoskeleton's precise architectural plan in fission yeast. The image of this unicellular organism will be published in this week's issue of the journal Developmental Cell and reveals remarkable insights into the fine structure of the cytoskeleton as well as its interactions with other parts of the cell.

Microbiology

UC Irvine researchers have combined genetic and geographic data of the H5N1 avian flu virus to reconstruct its history over the past decade. They found that multiple strains of the virus originated in the Chinese province of Guangdong, and they identified many of the migration routes through which the strains spread regionally and internationally.

Molecular & Cell Biology

Having an out-of-body experience may seem far-fetched to some, but for those with arousal system disturbances in their brains, it may not be a far off idea that they could sense they were really outside their own body watching themselves. In previous studies of more than 13,000 Europeans, almost 6 percent said they have had such an out-of-body experience.

Health & Medicine

Body mass index, or BMI, long considered the standard for measuring the amount of fat in a person's body, may not be as accurate as originally thought, according to new research.

Biotechnology

Using genetic manipulation to modify the activity of a plant enzyme, researchers at the U.S. Department of Energy's Brookhaven National Laboratory have converted an unsaturated oil in the seeds of a temperate plant to the more saturated kind usually found in tropical plants. The research will be published online by the Proceedings of the National Academy of Sciences (PNAS) the week of March 5, 2007.