Researchers have discovered a cluster of 45 genes coding for antibacterial drug resistance in the bacterium, Acinetobacter baumannii, a major cause of hospital-acquired infections worldwide. The study was reported in the open-access journal PLoS Genetics.

Researchers for the first time have created a three-dimensional image of apolipoprotein E, a protein long associated with cardiovascular disease and more recently with Alzheimer's disease, as it appears when it is bound to fat-like substances known as lipids.

Molecular biologists, developmental biologists and computer scientists at the Universtity of Helsinki, Finland, came together to advance towards cracking the code for how gene expression is controlled. The results of this work are published in Cell, in January 2006.

Like a family of petty criminals gone wrong, researchers at the University of California, San Diego (UCSD) were surprised to find that bacterial pathogens found in a number of troublesome diseases are actually related. Not only that, their wrong-doing is carried out by disguising themselves, then hijacking their hosts.

A common virus that causes meningitis and heart inflammation takes a "back door" approach to evade natural barriers, then exploits biological signals to infect human cells. Broadening knowledge of how viruses cause infection, a new study describes elaborate methods that the virus has evolved to bypass the body's defenses.

With their feathery tuxedoes and charming Chilly Willy-waddle, penguins are the quintessence of cute. Small wonder they're featured in Coke commercials, movies like "Madagascar" and "March of the Penguins" and children's toys galore.

UCLA researchers knew - based on two clinical trials - that a subset of kidney cancer patients responded well to an experimental targeted therapy, but they didn't know why. If they could determine the mechanism behind the response, they would be able to predict which patients would respond and personalize their treatment accordingly.

A serendipitous comparison prompted by an old scientific image and involving an ancient but understudied molecule may lead to a new treatment strategy for injuries or illnesses in which blood clotting is paramount to survival.

It may be no surprise that marine reserves protect the fish that live in them, but now scientists from the University of Exeter have shown for the first time that they could also help improve the health of coral reefs.