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Molecular & Cell Biology

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C. elegans is less than a millimeter in length and completely transparent. In the hermaphrodite, sex-cell division takes place within the tubelike arms of the gonad. As cell nuclei move through them, every stage of meiosis can be observed under the microscope.
Most cells in the body contain two copies of every chromosome, one from each parent. Sex involves gently scrambling the genetic material of the chromosomes to produce variations within each species, creating individuals variously equipped to meet life's challenges. The secret of sex is meiosis, a specialized kind of cell division in which a cell replicates and then divides twice (not just once, as nonsex cells do), resulting in sperm or eggs with just one set of chromosomes each.

Biology

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Studying fish, like this ocean sulfish, scientists are revealing the link between evolution and a species' genome. (Photo courtesy: Earthwindow.com/Mike Johnson)
Biologists at Georgia Tech have provided scientific support for a controversial hypothesis that has divided the fields of evolutionary genomics and evolutionary developmental biology, popularly known as evo devo, for two years. Appearing in the December 2005 issue of Trends in Genetics, researchers find that the size and complexity of a species' genome is not an evolutionary adaptation per se, but can result as simply a consequence of a reduction in a species' effective population size.

Microbiology

The ubiquitous and usually harmless E. coli bacterium, which has one-seventh the number of genes as a human, has more than 1,000 of them involved in metabolism and metabolic regulation. Activation of random combinations of these genes would theoretically be capable of generating a huge variety of internal states; however, researchers at UCSD will report in the Dec. 27 issue of Proceedings of the National Academy of Sciences (PNAS) that Escherichia coli doesn't gamble with its metabolism.

Biology

Bats have an "ear" for flying in the dark because of a remarkable auditory talent that allows them to determine their physical environment by listening to echoes. But an Ohio University neurobiology professor says bats have a "feel" for it, too.

Biotechnology

Ohio State University researchers have invented a process for uncoiling long strands of DNA and forming them into precise patterns.

Bioinformatics

Through the Human Genome Project, the HapMap Project and other efforts, we are beginning to identify genes that are modified in some diseases. More difficult to measure and identify are the regulatory regions in DNA – the 'managers' of genes – that control gene activity and might be important in causing disease.

Biology

The brain's ability to reorganize itself - strengthening or weakening connections between neurons or adding or subtracting those connections - allows it to form memories, make transitions between sleep and waking, and focus attention on objects of interest.

Microbiology

New research by a team of scientists in France and the United States has identified both the bacterial and host receptor proteins that enable Rickettsia conorii, the Mediterranean spotted fever pathogen, to enter cells. Understanding how this bacterium interacts with the cells of its host could lead to new therapeutic strategies for diseases caused by related pathogens, including Rocky Mountain spotted fever and typhus.

Environment

Buoyed by the effects of an intense drought, otherwise harmless snails likely killed off thousands of acres of salt marsh in the Southeast in recent years.