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Biology

In the Nov. 18 issue of Cell, researchers report the discovery of a gene that controls the ability to react with appropriate fear to impending danger. As a result, mice lacking the gene stathmin become daredevils of a sort, the researchers report. The basic findings may have general implications for the study of anxiety disorders and potential anti-anxiety drugs, according to researchers.

Molecular & Cell Biology

A counterintuitive experiment has resulted in one of the longest recorded life-span extensions in any organism and opened a new door for anti-aging research in humans.

Environment

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The half-tonne instrument platform supports a variety of oceanic sensors that will take measurements at regular intervals.
A project led by the University of Victoria is about to make oceanographic history. VENUS, the world's most advanced, cabled seafloor observatory, will be installed in December 2005 in the waters of Saanich Inlet north of Victoria, British Columbia.

Stem Cell Research

Northwestern University researchers have demonstrated how the microenvironments of two human embryonic stem cell (hESC) lines (federally approved) induced metastatic melanoma cells to revert to a normal, skin cell-like type with the ability to form colonies similar to hESCs. The researchers also showed that these melanoma cells were less invasive following culture on the microenvironments of hESCs.

Environment

A satellite surveillance zone within the southern Indian Ocean is helping protect the endangered Patagonian toothfish from pirate fishing vessels.

Microbiology

Like waves of soldiers guarding a castle gate, multiple genetic defenders cooperate to protect plant cells against powdery mildew disease, according to a new study. Powdery mildew is a common fungal infection in plants that attacks more than 9,000 species, including many crops such as barley and wheat, and horticultural plants such as roses and cucumbers. The researchers, including Shauna Somerville and Mónica Stein of the Carnegie Institution's Department of Plant Biology, are the first to document how these defense genes team up in plants. The discovery could help combat fungal parasites that devastate crops and cost growers billions of dollars in pesticides every year.

Bioinformatics

Researchers at The University of Arizona's plant sciences department and UA's BIO5 Institute have received a $29 million federal grant as part of a consortium to unlock the genetic code of the corn plant. The knowledge gained from the Maize Genome Sequencing Project will enable plant scientists and breeders to improve agronomically important traits in cereal crops more rapidly.

Health & Medicine

Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body.

Biology

New brain imaging research at the University of North Carolina at Chapel Hill indicates that when people with autism look at a face, activity in the brain area that responds is similar to that of people without autism.