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Microbiology

A malaria vaccine remains the most desired tool to combat the worsening malaria epidemic in many developing countries. Pierre Druilhe and colleagues (from the Institut Pasteur in Paris) have completed the first human trial of a vaccine based on MSP3, a protein present on the surface of the malaria parasite, with very encouraging results.

Microbiology

In some cases, the fusion of human cells is a normal process that leads, for instance, to the formation of muscle and bone. Viral infections can also cause cell fusion, but cells fused by viruses are widely considered to be harmless because they are generally believed to die without consequences for the host. According to a recent study, however, cell fusion triggered by viruses is a possible contributing factor in the development of human cancer. The study also raises concerns about the use fusogenic viruses as vectors for human gene therapy or in other clinical applications owing to the possibility that such viruses might cause cancer.

Biology

A team of scientists is proposing that endangered California condors raised in captivity be released near seal and sea lion rookeries so that the birds can once again feast on the carcasses of marine mammals as their ancestors did centuries ago.

Health & Medicine

Habitual coffee drinking is not associated with an increased risk of hypertension in women, although an association was found with the consumption of sugared or diet colas, according to a study in the November 9 issue of JAMA.

Health & Medicine

Phenolic compounds in olive oil, which have antioxidant, anti-inflammatory and anti-clotting properties, may explain cardiovascular health benefits associated with the so-called Mediterranean Diet, according to a new study in the Nov. 15, 2005, issue of the Journal of the American College of Cardiology.

Biotechnology

Three young scientists in the University of York's Department of Chemistry have developed a gel that could spare cancer patients some of the unpleasant and dangerous side-effects of radiotherapy.

Health & Medicine

Physicians prescribe antibiotics for more than half of children with sore throat, exceeding the expected prevalence of strep throat, and used nonrecommended antibiotics for 27 percent of children who received an antibiotic prescription, according to a study in the November 9 issue of JAMA.

Microbiology

In a groundbreaking, sure-to-be-controversial new study, Emily Oster (a graduate student in economics at Harvard University) argues that excess female mortality, such as infanticide, may not be the only cause of uncommonly high male to female ratios in many Asian countries. It has long been observed that the relative number of males is higher in certain Asian countries than in the West, where it is close to unity. A number of authors have suggested that this imbalance reflects neglect of female children and poor conditions for women and, as a result, have argued that as many as 100 million women are "missing."

Molecular & Cell Biology

The Quaking gene, first described as a mutation in mice that causes rapid tremor, is thought to suppress tumor formation and protect humans from cancer.

Health & Medicine

The good news is that medical advances in perinatal care have allowed us to save many more premature babies. The bad news is they're often at risk of developing bronchopulmonary dysplasia--a chronic lung disease caused by having to place the tiny infants on ventilators and oxygen-rich therapy for acute respiratory failure.