Health & Medicine

Dr Alex Mesoudi, from Queen Mary's newly established Research Centre for Psychology, has found evidence that the increasing reach and influence of the media, combined with a growing number of people assigned celebrity status, could increase the probability of widespread suicide pandemics. The study is published today in the peer reviewed journal PLoS ONE.

Biology

According to the AZTI-Tecnalia researchers, the first estimations of the geographical location of the recovered tag revealed that this fish had undertaken migrations between the Azores and Portugal during the winter, later to return to the Gulf of Bizkaia in spring and also that it had dived, during the winter, to depths of more than 1000 metres.

Health & Medicine

A study led by researchers at the University of California, Berkeley, has identified critical biochemical pathways linked to the aging of human muscle. By manipulating these pathways, the researchers were able to turn back the clock on old human muscle, restoring its ability to repair and rebuild itself.

Health & Medicine

MassBiologics of the University of Massachusetts Medical School today announced the beginning of a Phase 1 clinical trial, testing the safety and activity of a human monoclonal antibody (MAB) developed to neutralize the rabies virus.

Environment

It's not every day you find clues to the planet's inner workings in aquarium scum. But that's what happened a few years ago when University of Washington researchers cultured a tiny organism from the bottom of a Seattle Aquarium tank and found it can digest ammonia, a key environmental function. New results show this minute organism and its brethren play a more central role in the planet's ecology than previously suspected.

Biology

You can learn a lot from an animal. By manipulating the DNA of mice, flies, frogs and worms, scientists have discovered a great deal about the genes and molecules behind many of life's essential processes. These basic functions often work about the same in people as they do in "model" animals. But if you want to study more sophisticated cognitive processes such as humans' ability to learn language from one another, you need a more sophisticated organism. For the first time, researchers have devised a way to alter the genes of the zebra finch, one of a handful of social animals that learn to "speak" by imitating their fellows.

Molecular & Cell Biology

Chaos brews in the brains of newborns: the nerve cells are still bound only loosely to each other. Under the leadership of Academy Research Fellow Sari Lauri, a team of researchers at the University of Helsinki has been studying for years how a neural network capable of processing information effectively is created out of chaos. The team has now found a new kind of mechanism that adjusts the functional development of nerve cell contacts. The results were published in early September as the leading article of the esteemed Journal of Neuroscience.

Biology

When pondering the demise of a famous dinosaur such as 'Sue,' the mighty Tyrannosaurus rex whose fossilized remains are a star attraction of the Field Museum in Chicago, it is hard to avoid the image of clashing Cretaceous titans engaged in bloody, mortal combat.

Australian researchers have discovered a huge number of new species of invertebrate animals living in underground water, caves and "micro-caverns" amid the harsh conditions of the Australian outback.

Health & Medicine

Current research suggests that the inflammatory molecule TNF-α may contribute to delayed bone fracture healing in diabetics. The related report by Alblowi et al, "High Levels of TNF-α Contribute to Accelerated Loss of Cartilage in Diabetic Fracture Healing" appears in the October 2009 issue of the American Journal of Pathology.

Health & Medicine

A study conducted in Vietnam has added further weight to the view that parasitic gut worms, such as hookworm, could help in the prevention and treatment of asthma and other allergies.

Health & Medicine

Vincent van Gogh cut off his ear. Sylvia Plath stuck her head in the oven. History teems with examples of great artists acting in very peculiar ways. Were these artists simply mad or brilliant? According to new research reported in Psychological Science, a journal of the Association for Psychological Science, maybe both.

Health & Medicine

Lowers blood pressure, encourages exercise, improves psychological health— these may sound like the effects of a miracle drug, but they are actually among the benefits of owning a four-legged, furry pet. This fall, the University of Missouri College of Veterinary Medicine Research Center for Human-Animal Interaction (ReCHAI) will explore the many ways animals benefit people of all ages during the International Society for Anthrozoology and Human-Animal Interaction Conference in Kansas City, Mo., on Oct. 20-25.

Biology
BiologySeptember 29, 2009 01:19 AM

There may be plenty of fish in the sea but the medaka knows what it likes. A new study published in the open access journal BMC Biology shows how a single gene mutation that turns Japanese Killifish a drab grey colour renders them significantly less attractive to more colourful members of the opposite sex.

Health & Medicine

Will neglecting to brush your teeth damage more than just your smile? Can failing to attack dental plaque increase your risk of heart damage?

The Potato Genome Sequencing Consortium (PGSC), an international team of scientists from industry and academia in 14 countries, has released a draft sequence of the potato genome with the help of a Virginia Tech researcher.

Health & Medicine

Although it has been demonstrated that Helicobacter pylori causes gastric cancer, it is still controversial that whether H. pylori eradication therapy is effective in primary prevention of gastric cancer. This is especially important for Yamagata Prefecture, a region of Japan with the second highest incidence of gastric cancer in the world.

Biology

Today's Scandinavians are not descended from the people who came to Scandinavia at the conclusion of the last ice age but, apparently, from a population that arrived later, concurrently with the introduction of agriculture. This is one conclusion of a new study straddling the borderline between genetics and archaeology, which involved Swedish researchers and which has now been published in the journal Current Biology.

Biology
BiologySeptember 25, 2009 12:33 AM

Do infants only start to crawl once they are physically able to see danger coming? Or is it that because they are more mobile, they develop the ability to sense looming danger? According to Ruud van der Weel and Audrey van der Meer, from the Norwegian University of Science and Technology in Trondheim, infants' ability to see whether an object is approaching on a direct collision course, and when it is likely to collide, develops around the time they become more mobile. Their findings (1) have just been published online in the Springer journal Naturwissenschaften.

Health & Medicine

Berlin, Germany: At least 124,000 new cancers in 2008 in Europe may have been caused by excess body weight, according to estimates from a new modelling study. The proportion of cases of new cancers attributable to a body mass index of 25kg/m2 or more were highest among women and in central European countries such as the Czech Republic, Latvia, Slovenia and Bulgaria.

Microbiology

Five genetic regions have been identified that are unique to the most virulent strain of Clostridium difficile (C. difficile), the hospital superbug. Researchers writing in BioMed Central's open access journal Genome Biology studied the genome of the bacterium, looking for genes relating to motility, antibiotic resistance and toxicity.

Biology

When the ancestors of living cetaceans—whales, dolphins and porpoises—first dipped their toes into water, a series of evolutionary changes were sparked that ultimately nestled these swimming mammals into the larger hoofed animal group. But what happened first, a change from a plant-based diet to a carnivorous diet, or the loss of their ability to walk? A new paper published this week in PLoS One resolves this debate using a massive data set of the morphology, behavior, and genetics of living and fossil relatives. Cetacean ancestors probably moved into water before changing their diet (and their teeth) to include carnivory; Indohyus, a 48-million year-old semi-aquatic herbivore, and hippos fall closest to cetaceans when the evolutionary relationships of the larger group are reconstructed.

Biology
BiologySeptember 25, 2009 12:33 AM

By carefully observing and analyzing the pattern of activity in the brain, researchers have found that they can tell what number a person has just seen. They can similarly tell how many dots a person has been presented with, according to a report published online on September 24th in Current Biology, a Cell Press publication.

Biology

When it comes to understanding a critical junction in animal evolution, some short, simple flatworms have been a real thorn in scientists' sides. Specialists have jousted over the proper taxonomic placement of a group of worms called Acoelomorpha. This collection of worms, which comprises roughly 350 species, is part of a much larger group called bilateral animals, organisms that have symmetrical body forms, including humans, insects and worms. The question about acoelomorpha, was: Where do they fit in?

Biology

A new study explores how our brains synthesize concepts that allow us to organize and comprehend the world. The research, published by Cell Press in the September 24th issue of the journal Neuron, uses behavioral and neuroimaging techniques to track how conceptual knowledge emerges in the human brain and guides decision making.

Health & Medicine

Walter and Eliza Hall Institute researchers are part of an international team that has discovered a genetic variation that could identify those people infected with hepatitis C who are most likely to benefit from current treatments.

Biotechnology

Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have uncovered what happens to biomimetic nanoparticles when they enter human cells. They found that the important proteins that make up the outer layer of these nanoparticles are degraded by an enzyme called cathepsin L. Scientists now have to take this phenomenon into account and overcome this process to ensure the exciting field of nanomedicine can progress. The research is published today (22 September) in ACS Nano.

September 21, 2009 06:25 PM

When a whale dies, it sinks to the seafloor and becomes food for an entire ecosystem. Researchers at the University of Gothenburg, Sweden, have discovered previously unknown species that feed only on dead whales - and use DNA technology to show that the species diversity in our oceans may be higher than previously thought.

Molecular & Cell Biology

- We now begin to understand how signalling proteins recognize and transport to certain areas of the cell and get a more clear insight on the mechanism of major cellular processes such as cell signalling and growth. This valuable knowledge could be used in the future to understand and cure disease such as depression and Alzheimer's explains Associate Professor Dimitrios Stamou, Nano-Science Center and Department of Neuroscience and Pharmacology, who led the work.

Health & Medicine

An investigative drug deprived non-Hodgkin lymphoma cells of their ability to survive too long and multiply too fast, according to an early study published recently in the journal Experimental Hematology.

AIDS & HIV

Scientists working to develop a vaccine for the human immunodeficiency virus (HIV) report they have created the first antigen that induces protective antibodies capable of blocking infection of human cells by genetically-diverse strains of HIV. The new antigen differs from previously-tested vaccines by virtue of its chemically-activated property that enables close sharing of electrons and produces strong covalent bonding. Researchers used a mouse model to generate the antibodies. The report by researchers at The University of Texas Health Science Center at Houston is online and will appear in a print issue of the Journal of Biological Chemistry in November.

Molecular & Cell Biology

Investigators at Burnham Institute for Medical Research (Burnham) have identified novel cleavage sites for the enzyme caspase-3 (an enzyme that proteolytically cleaves target proteins). Using an advanced proteomic technique called N-terminomics, Guy Salvesen, Ph.D., professor and director of the Apoptosis and Cell Death Research program of Burnham's NCI-designated Cancer Center, and colleagues determined the cleavage sites on target proteins and found, contrary to previous understanding, that caspase-3 targets α-helices as well as unstructured loops. In addition, researchers found that caspase-3 and the substrates it binds to co-evolved. The paper was published on September 20 in the journal Nature Structural & Molecular Biology.

Health & Medicine

Scientists have found that some individuals in the vegetative and minimally conscious states, despite lacking the means of reporting awareness themselves, can learn and thereby demonstrate at least a partial consciousness. Their findings are reported in today's (20 September) online edition of Nature Neuroscience.

Health & Medicine

UCLA researchers have discovered that a combination of drugs, electrical stimulation and regular exercise can enable paralyzed rats to walk and even run again while supporting their full weight on a treadmill.

Molecular & Cell Biology

Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have shown that a common biological protein molecule called SHP-2 is crucial for encouraging placenta growth. The research is published today in Endocrinology.

Biology

Bugs in boxes are helping University of California, Davis, researcher Alan Hastings improve scientific tools used to predict the spread of invasive plants and animals.

Biotechnology

Many medical conditions, such as chronic pain, cancer and diabetes, require medications that cannot be taken orally, but must be dosed intermittently, on an as-needed basis, over a long period of time. A few delivery techniques have been developed, using an implanted heat source, an implanted electronic chip or other stimuli as an "on-off" switch to release the drugs into the body. But thus far, none of these methods can reliably do all that's needed: repeatedly turn dosing on and off, deliver consistent doses and adjust doses according to the patient's need.

Health & Medicine

A person, usually a child, dies of rabies every 20 minutes. However, only one inoculation may be all it takes for rabies vaccination, according to new research published in the Journal of Infectious Diseases by researchers at the Jefferson Vaccine Center.

Molecular & Cell Biology

Many of the genes that regulate insulin also alter the timing of the circadian clock, a new study has found.

Biology

Spanish scientists have developed a model to identify the agricultural areas with the greatest potential for restoring the habitat of the Iberian lynx (Lynx pardinus), which is at risk of extinction. The study shows that olive groves with low production close to the Natural Park of the Sierra de Cardeña y Montoro, in Córdoba – which is the only place, along with Doñana, where this species lives – are the most appropriate sites for this purpose.




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