By applying the techniques of computer engineering to a mechanistic diagram describing the development of the Nematode C. elegans, a group of researchers in Switzerland has been able to tease out what laboratory experiments have not – how and when the crucial cross-talk between cellular signaling pathways takes place in order to determine the fates of individual cells. The novel in silico model is described in a paper appearing May 18, 2007 in the open-access journal PLoS Computational Biology.

