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Molecular & Cell Biology

Skin is our first line of defense against infection. But people with a rare, life-threatening autoimmune disease called pemphigus vulgaris lack that protection because their immune system attacks the proteins that hold skin cells together. They develop severe blisters and raw sores as the top layer of their skin falls apart, leaving them extremely vulnerable to infection.

Health & Medicine

Patented NASA technology that originally enhanced robotics and sounding rockets is now aiding U.S. soldiers returning from overseas duty with spinal cord or traumatic brain injuries, at Walter Reed Army Medical Center in Washington, D.C. The revolutionary new physical therapy device named SAM, for the Secure Ambulation Mode, is based on technology originally developed and honed at NASA's Goddard Space Flight Center in Greenbelt, Md.

Health & Medicine

A study by cancer researchers here reveals that a new strain of mice offers the first real animal model for an incurable form of chronic leukemia and should greatly aid the development of new drugs for the disease.

Molecular & Cell Biology

A new breed of permanently 'cheerful' mouse is providing hope of a new treatment for clinical depression. TREK-1 is a gene that can affect transmission of serotonin in the brain. Serotonin is known to play an important role in mood, sleep and sexuality. By breeding mice with an absence of TREK-1, researchers were able create a depression-resistant strain. The details of this research, which involved an international collaboration with scientists from the University of Nice, France, are published in Nature Neuroscience this week.

Molecular & Cell Biology

Cigarette smoke can turn normal breast cells cancerous by blocking their ability to repair themselves, eventually triggering tumor development, University of Florida scientists report.

Molecular & Cell Biology

Scientists at the University of York have made a huge leap forward in the search for 'smarter' antibiotics.

Molecular & Cell Biology

Water, that molecule-of-all-trades, is famous for its roles in shaping the Earth, sustaining living creatures and serving as a universal solvent.

Biotechnology

UC Davis researchers have successfully used a custom designed protein and gene delivery system to restore normal heart rhythms in pigs with electronic pacemakers, reducing their dependence on implanted devices. This work suggests that scientists are one step closer to making bioengineering a reality in treating the more than 2.2 million Americans affected by irregular heartbeats.