Massachusetts General Hospital (MGH) researchers have identified potential ovarian cancer stem cells, which may be behind the difficulty of treating these tumors with standard chemotherapy. Understanding more about the stem-like characteristics of these cells could lead to new approaches to treating ovarian cancer, which kills more than 16,000 U.S. women annually and is their fifth most common cause of cancer death. The report will appear in the July 25 Proceeding of the National Academy of Sciences (PNAS) and has received early online release.

Albuquerque, N.M. -- Far above the heads of Earthlings, arrays of single-cell creatures are circling Earth in nanostructures.

While studying how a cell keeps its genetic material intact, scientists at Johns Hopkins got busy alternately knocking out two catalysts vital to managing a yeast cell's energy. They discovered to their complete surprise that the removal of one of them led the cell to turn off 70 percent of its 5,000 genes and die.

Attempts to identify potential drugs that interfere with the action of one particular enzyme linked to heart disease and similar health problems led scientists at Johns Hopkins to create a new tool and new experimental approach that allow them to see multiple, real-time chemical reactions in living cells. Their report on the work is published July 21 in the journal ACS Chemical Biology.

Ten years ago, an international team of scientists reported evidence, in a controversial cover story in the journal Nature, that life on Earth began more than 3.8 billion years ago--400 million years earlier than previously thought. A UCLA professor who was not part of that team and two of the original authors will report in late July that the evidence is stronger than ever.

For over a decade, the technique of distraction has been researched and successfully applied in clinical practice in order to reduce pain associated with certain medical procedures. The use of distraction is based on the assumption that there is an important psychological element in the perception of pain, with the amount of attention given to the harmful stimulus affecting the perception of the pain.

University of Minnesota researchers have discovered how a prevalent fungal pathogen that causes 10,000 deaths per year in the United States overcomes the effects of antifungal drugs by duplicating a section of one of its chromosomes.

Researchers at Rice University's Laboratory for Nanophotonics (LANP) have unveiled the "nanoegg," the latest addition to their family ultrasmall, light-focusing particles. A cousin of the versatile nanoshell, nanoeggs are asymmetric specks of matter whose striking optical properties can be harnessed for molecular imaging, medical diagnostics, chemical sensing and more.

Researchers at the National Institute of Standards and Technology (NIST) have demonstrated the use of water droplets as minuscule "boxes" for small numbers of biomolecules. The unusually simple containment method may enable easier experiments on single molecule dynamics and perhaps lead to the development of molecule-sorting devices that might be used for medical screening or biotechnology research. The work was reported in the July 3 issue of Applied Physics Letters.

The diversity of bees and of the flowers they pollinate, has declined significantly in Britain and the Netherlands over the last 25 years according to research led by the University of Leeds and published in Science this Friday (21 July 2006). The paper is the first evidence of a widespread decline in bee diversity.