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Biology

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The silverside, having been reared for five generations in laboratory experiments, are all the same age. The fish on the left are from populations from which large individuals were harvested over five generations; the fish in the middle are from populations from which fish were harvested at random over five generations; and the fish on the right are from populations from which only small fish were harvested over five generations. Photo credit: M. Walsh.
The practice of harvesting the largest individuals from a fish population introduces genetic changes that harm the overall fish population, a UC Riverside graduate student and colleagues have determined. Removing the large fish over several generations of fish causes the remaining fish in the populations to become progressively smaller, have fewer and smaller eggs with lower survival and growth, and have lower foraging and feeding rates, the researchers report.

Health & Medicine

In a multifaceted study involving the Kuna Indians of Panama, an international team of scientists has pinpointed a chemical compound that is, in part, responsible, for the heart-healthy benefits of certain cocoas and some chocolate products.

Microbiology

Dirt may be a key to how bacteria that infect humans develop a resistance to antibiotic drugs.

Health & Medicine

Drug discovery researchers at Northwestern University have developed a novel orally administered compound specifically targeted to suppress brain cell inflammation and neuron loss associated with Alzheimer's disease.

Health & Medicine

Drugs that treat depression by manipulating the neurotransmitter serotonin in the brain may also affect the user's immune system in ways that are not yet understood, say scientists from Georgetown University Medical Center and a Canadian research institute.

Biology

Scientists are interested in understanding genetic control of grass inflorescence architecture because seeds of cereal grasses (e.g. rice, wheat, maize) provide most of the world's food.

Molecular & Cell Biology

A Mayo Clinic-led research collaboration has discovered that the protein MDC1 amplifies weak DNA injury signals so genetic repair can begin. Once amplified, even low-level damage signals become strong enough to activate the cell's natural repair processes while the injury is most tractable to repair.

Biotechnology

Scientists at Virginia Tech have developed a single-step process for creating nonwoven fibrous mats from a small organic molecule – creating a new nanoscale material with potential applications where biocompatible materials are required, such as scaffolds for tissue growth and drug delivery.

Environment

Scientists at the UK's leading plant science centre have uncovered a gene that could help to develop new varieties of crop that will be able to cope with the changing world climate. Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) at the John Innes Centre in Norwich have identified the gene in barley that controls how the plant responds to seasonal changes in the length of the day. This is key to understanding how plants have adapted their flowering behaviour to different environments.