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Biology

There's hope for the less-than-perfect male – if you're a swordtail fish, that is. As the size and age of female swordtail fish increase, so does the preference for males with asymmetrical markings, according to a new Ohio University study.

Stem Cell Research

New experiments that prevented rat sperm stem cells from changing permanently into sperm have brought researchers one step closer to coaxing such cells to behave like embryonic stem cells, capable of growing into many other types of cells in the body.

Biology

An international team of scientists for the first time has detected a memory trace in a living animal after it has encountered a single, new stimulus. The research, done with honeybees sensing new odors, allows neuroscientists to peer within the living brain and explore short-term memory as never before, according to scientist Roberto Fernández Galán, a leading author on the report who is currently a postdoctoral research associate at Carnegie Mellon University.

Gene Therapy

A gene responsible for the production of a protein called vasostatin may prove a promising new way of treating pancreatic cancer, suggests research published ahead of print in Gut.

Biotechnology

Using transparent zebrafish embryos, researchers at Jefferson Medical College have shown that a microscopic nanoparticle can help fend off damage to normal tissue from radiation. The nanoparticle, a soccer ball-shaped, hollow, carbon-based structure known as a fullerene, acts like an "oxygen sink," binding to dangerous oxygen radicals produced by radiation.

Microbiology

An anti-cancer compound derived from bacteria dwelling in ocean-bottom sediments appears in laboratory tests to be a potent killer of drug-resistant multiple myeloma cells, and potentially with less toxicity than current treatments, report Dana-Farber Cancer Institute researchers in the November issue of Cancer Cell.

Molecular & Cell Biology

Forsyth Institute research with the flatworm, planaria, offers new clues for understanding restoration of body structures. Researchers at The Forsyth Institute have discovered how the worm's cells communicate to correctly repair and regenerate tissue. Forsyth scientists have found that gap-junction (microscopic tunnels directly linking neighboring cells) communication contributes to this signaling. This research, led by Dr. Michael Levin, underlies principles that can potentially offer insight into human regeneration.

Microbiology

Tuberculosis (TB) is the most common major infectious disease today. It is estimated that two billion people--or one-third of the world's population--are chronically infected without active symptoms. Nine million new cases of active disease are diagnosed annually, resulting in two million deaths. TB is predominantly a lung disease. It is caused by a microbe called Mycobacterium tuberculosis which infects lung cells, but it is still not clear how exactly this happens. Ludovic Tailleux, Olivier Neyrolles, and colleagues (from the Pasteur Institute, in collaboration with the Necker and Saint-Louis Hospitals, in Paris) have found that a molecule called DC-SIGN plays a crucial part.