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Stem Cell Research

The growth and maintenance of human embryonic stem cells in the absence of contaminated animal products has been demonstrated by University of California, San Diego (UCSD) School of Medicine researchers in the Whittier Institute, La Jolla, California.

Biotechnology

Every protein--from albumin to testosterone (Ed : testosterone isn't a protein, it's a steroid)--is folded into a unique, three-dimensional shape that allows it to function properly. Now Stanford University scientists have developed a simple test that instantly changes color when a protein molecule attached to a gold nanoparticle folds or unfolds. The new technique, which works on the same principle as ordinary pH tests that measure the acidity of water, is described in the March 2005 issue of the journal Chemistry and Biology.

Stem Cell Research

Researchers at Children's Hospital Boston and the Dana-Farber Cancer Institute report a surprising finding about embryonic development: the blood system begins to form not only in the embryo itself, but also in the placenta, the organ that nurtures the baby in utero.

Biotechnology

For all its promise, the prospect of using nanoparticles in biomedical applications and consumer products has raised concerns about possible harmful effects of the miniscule materials. Scientists at the University of Michigan are addressing those concerns by investigating how certain kinds of nanoparticles damage cell membranes—enough to cause cell death in some cases—and how the damage can be prevented.

Microarray

Nanogen, Inc. (Nasdaq: NGEN), developer of advanced diagnostic products, announced today that it was issued U.S. Patent No. 6,867,048, "Multiplexed Active Biologic Array" by the U.S. Patent and Trademark Office. The '048 patent relates to a method of addressing one or more electrodes (or "test sites") across multiple rows and columns of a microarray. The patent also covers a method for storing the value of the voltage associated with each electrode in a local memory. This "smart chip" technology is a key feature of Nanogen's NanoChip(R) 400 electronic microarray, the company's second generation multi-purpose system for developing and performing molecular diagnostic tests.