This image shows Yucca Brevifolia Tikaboo, June 2014. Scientists at the Donald Danforth Plant Science Center have teamed up with researchers at Willamette University, a liberal arts college in Salem Oregon, to develop genetic tools that could save the Joshua tree from extinction. Together with scientists from The University of Georgia and the University of British Columbia, and with the support of several Mojave Desert conservation organizations, researchers are inviting members of the public to help get the project off the ground by making donations at the crowdfunding site Experiment.com. In the past two weeks, more than 100 backers have donated more than $4,000 to The Joshua Tree Genome Project. The project aims to raise $8,500 by March 24th.

This is the cover of Protein & Cell. The human brain is extremely complex, containing billions of neurons forming trillions of synapses where thoughts, behavior and emotion arise. However, when an individual is performing a particular task, not many but only a few neural circuits are in action. The enormous cellular heterogeneity of the brain structure has made dissections of the molecular basis for neural circuitry function particularly challenging, because previous studies on genetic and epigenetic profiling using a block of brain tissues simply do not have the sufficient precision and accuracy to correspond to the activities of a few activated circuitries in the brain.