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Biology

Tiny fossilized teeth excavated from an Indian open-pit coal mine could be the oldest Asian remains ever found of anthropoids, the primate lineage of today's monkeys, apes and humans, say researchers from Duke University and the Indian Institute of Technology.

Health & Medicine

An independent link between sleep apnea and mortality has been discovered by a group of Australian researchers, suggesting the prevention and treatment of this condition should be a higher priority for government bodies working to improve community health.

Health & Medicine

Positive findings of a safety study involving children and a highly touted botanical extract (COLD-fX) show promise for its future development for kids as a Canadian cold and flu remedy. The results appear in the August, 2008 issue of Pediatrics – the official journal of the American Academy of Pediatrics.

Biology

Using sophisticated computer modelling techniques they have also calculated that the bite force of the great white's extinct relative, the gigantic fossil species Carcharodon megalodon (also known as Big Tooth) is the highest of all time, making it arguably the most formidable carnivore ever to have existed.

AIDS & HIV

Patients receiving rifampicin-based anti-tuberculosis therapy are more likely to experience virological failure when starting nevirapine-based antiretroviral therapy, an HIV treatment that is widely used in developing countries because of lower cost, than when starting efavirenz-based antiretroviral therapy, according to a study in the August 6 issue of JAMA, a theme issue on HIV/AIDS.

Biology


The snake named Leptotyphlops carlae, as thin as a spaghetti noodle, is resting on a US quarter.
The world's smallest species of snake, with adults averaging just under four inches in length, has been identified on the Caribbean island of Barbados. The species -- which is as thin as a spaghetti noodle and small enough to rest comfortably on a U.S. quarter --was discovered by Blair Hedges, an evolutionary biologist at Penn State. Hedges and his colleagues also are the discoverers of the world's smallest frog and lizard species, which too were found on Caribbean islands. The most recent discovery will be published on 4 August 2008 in the journal Zootaxa.

Health & Medicine

High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the National Institutes of Health (NIH) report in the August 5, 2008, issue of the Proceedings of the National Academy of Sciences. The researchers traced ascorbate's anti-cancer effect to the formation of hydrogen peroxide in the extracellular fluid surrounding the tumors. Normal cells were unaffected.

Molecular & Cell Biology

Researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech have identified the region of a large family of virulence proteins in oomycete plant pathogens that enables the proteins to enter the cells of their hosts. The protein region contains the amino acid sequence motifs RXLR and dEER and has the ability to carry the virulence proteins across the membrane surrounding plant cells without any additional machinery from the pathogen. Once inside the plant cell, the proteins suppress the immune system of the plant allowing the infection to progress. The work, which focused on the virulence protein Avr1b from the soybean plant pathogen Phytophthora sojae, is published in the advance online edition of The Plant Cell.*

Bioinformatics

Stanford University researchers peering at history's footprints on human DNA have found new evidence for how prehistoric people shared knowledge that advanced civilization.




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