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Molecular & Cell Biology

In a new study in PLoS Medicine, Samir Hanash and colleagues from Fred Hutchinson Cancer Research Center in Seattle report the identification of proteins that appear in increased numbers at an early stage of pancreatic tumor development in a mouse model and may be a useful tool in detecting early tumors in humans.

Health & Medicine

Amid recent reports of dangerous levels of arsenic being found in some baby rice products, scientists have found a protein in plants that could help to reduce the toxic content of crops grown in environments with high levels of this poisonous metal. Publishing in the open access journal BMC Biology, a team of Scandinavian researchers has revealed a set of plant proteins that channel arsenic in and out of cells.

Biology

A team of forensic scientists at the University of Copenhagen has studied human remains found in two ancient Danish burial grounds dating back to the iron age, and discovered a man who appears to be of arabian origin. The findings suggest that human beings were as genetically diverse 2000 years ago as they are today and indicate greater mobility among iron age populations than was previously thought. The findings also suggest that people in the Danish iron age did not live and die in small, isolated villages but, on the contrary, were in constant contact with the wider world.

Health & Medicine

Good dental hygiene and health may be crucial in preventing heart valve infection, according to research reported in Circulation: Journal of the American Heart Association.

Microbiology

By disrupting the potassium channel of the malaria parasite, a team of researchers has been able to prevent new malaria parasites from forming in mosquitoes and has thereby broken the cycle of infection during recent animal tests.

Environment

New evidence that chemical contaminants are finding their way into the deep-sea food web has been found in deep-sea squids and octopods, including the strange-looking "vampire squid". These species are food for deep-diving toothed whales and other predators.

Health & Medicine

University of Illinois at Chicago researchers have modified the procedure for islet cell transplantation and achieved insulin independence in diabetes patients with fewer but better-functioning pancreatic islet cells.

Molecular & Cell Biology

A new study demonstrates that microRNAs can modulate the expression of well known tumor-specific oncogenic translocation proteins and may play a significant role in some human cancers. The research, published by Cell Press in the June issue of the journal Cancer Cell, is likely to lead to new strategies for treating some specific lymphomas and leukemias.

Health & Medicine

A 115-year-old woman who remained mentally alert throughout her life had an essentially normal brain, with little or no evidence of Alzheimer's disease, according to a study in the August issue of Neurobiology of Aging (http://neurobiologyofaging.org/).

Health & Medicine

A clinical study on patients who have suffered a heart attack found that a partially purified extract of Chinese red yeast rice, Xuezhikang (XZK), reduced the risk of repeat heart attacks by 45%, revascularization (bypass surgery/angioplasty), cardiovascular mortality and total mortality by one-third and cancer mortality by two-thirds. The multicenter, randomized, double-blind study, was conducted on almost 5,000 patients, ranging in age from 18-70 over a five-year period at over 60 hospitals in the People's Republic of China. Corresponding author David M. Capuzzi, M.D., Ph.D, director of the Cardiovascular Disease Prevention Program at Jefferson's Myrna Brind Center of Integrative Medicine and Zonliang Lu, M.D., Ph.D, from the Fuwai Hospital at the Chinese Academy of Medical Science report their findings in the June 15th edition of the American Journal of Cardiology.