Infection with the fungus Candida parapsilosis is a major problem for individuals in intensive care units, as well as for premature infants and immunocompromised adults. Despite this, little is known about which of its genes account for its virulence. New insight into the virulence mechanisms of C. parapsilosis has now been provided by Attila Gacserand colleagues at the Albert Einstein College of Medicine, New York, who have developed a new way to eliminate genes in C. parapsilosis.

