A gene earlier linked to a rare disease plays a critical role in the body's "finely tuned balance" of fat storage and break down, new evidence reported in the May Cell Metabolism reveals. The findings elucidate the mechanism underlying healthy fat metabolism and explain why people with the genetic condition known as Chanarin-Dorfman Syndrome (CDS), who carry a mutant version of the gene, suffer from the widespread buildup of fat in tissues throughout their bodies.

