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[Business Office Feature] Chromatin untangled: New methods map genomic structure

ScienceNOW - Fetched: October 6th, 2016, 3:00pm UTC

With some 2 meters of DNA squished into the micron-sized nucleus of every mammalian cell, to call that space "cozy" is an understatement. Yet for cells, the genome poses issues not only of compaction but of functionality: The DNA must be packaged such that it remains accessible to gene regulatory factors. Indeed, chromatin architecture plays a key role in gene regulation, but until recently, researchers had few tools with which to study that relationship.Read the Feature (Full-Text HTML)Read the Feature (PDF)Read New Products (PDF) Author: Jeffrey M. Perkel

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