Glioblastoma is a notoriously difficult-to-treat brain cancer with an often poor prognosis. Virginia Tech Carilion Research Institute scientists are developing innovative cross-disciplinary therapies to treat the cancer. At the Virginia Tech Carilion Research Institute, three scientists are planning to create a virus capable of destroying brain cancer.

In order to develop new anti-cancer treatments, researchers need to identify target molecules that are responsible for controlling tumour growth. Two such molecules are JNK and p38, which both regulate cell multiplication and cell death.

A new study identifies a gene that is especially active in aggressive subtypes of breast cancer. The research suggests that an overactive BCL11A gene drives triple-negative breast cancer development and progression.

Dr. Jalees Rehman is an associate professor of medicine and pharmacology, UIC College of Medicine. Researchers at the University of Illinois at Chicago have discovered a novel molecular mechanism that tightens the bonds between the cells that line blood vessels to form a leak-proof barrier. The mechanism presents a potential new target to treat acute respiratory distress syndrome (ARDS), an often fatal condition in which fluid leaks out of blood vessels into the lungs.