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Molecular & Cell Biology

Massachusetts General Hospital (MGH) investigators have used a new sequencing method to identify a group of genes used by the brain's immune cells – called microglia – to sense pathogenic organisms, toxins or damaged cells that require their response. Identifying these genes should lead to better understanding of the role of microglia both in normal brains and in neurodegenerative disorders and may lead to new ways to protect against the damage caused by conditions like Alzheimer's and Parkinson's diseases. The study, which has been published online in Nature Neuroscience, also finds that the activity of microglia appears to become more protective with aging, as opposed to increasingly toxic, which some previous studies had suggested.

Environment

A University of Maryland-led, multi-organizational team has created the first high-resolution global map of forest extent, loss and gain. This resource greatly improves the ability to understand human and naturally-induced forest changes and the local to global implications of these changes on environmental, economic and other natural and societal systems, members of the team say.

http://earthenginepartners.appspot.com/science-2013-global-forest

Health & Medicine

American and European studies prove that students use prescription medication or drugs to enhance their cognitive performance. Researchers from the universities of Zurich and Basel examined whether Swiss students have also experimented with neuroenhancement and which substances they take by conducting a survey of 6,725 students with an average age of 23 at the two universities and ETH Zurich.