BioMed Central is pleased to announce the launch of Biology Direct, a new online open access journal with a novel system of peer review. Biology Direct will operate completely open peer review, with named peer reviewers' reports published alongside each article. The journal also takes the innovative step of requiring that the author approach Biology Direct Editorial Board members directly to review the manuscript.

Scientists have determined the detailed structure of an essential piece of the telomerase enzyme, an important contributor to the vast majority of human cancers. Understanding the physical shape of the protein has led to a better understanding of how it acts to immortalize cells – and should help scientists design broadly effective cancer drugs.

It may still be "king of the beasts," but the African lion's kingdom is dwindling, according to a new report released by the New York-based Wildlife Conservation Society (WCS) that says these emblematic big cats have disappeared from 82 percent of their historic distribution over the past several decades. The 200-page report looked at the conservation status of the 20 largest species of African carnivores and examined priorities to help ensure that they persist on the continent.

About five percent of deaths from SIDS (sudden infant death syndrome) in African Americans can be traced to defects in one gene and half of those deaths result from a common genetic variation that increases an infant's risk of developing an abnormal heart rhythm during times of environmental stress, a research team based at the University of Chicago reports in the February 2006 issue of the Journal of Clinical Investigation.

Longtime collaborators CONRAD and the Biosyn Division of Cellegy Pharmaceuticals, Inc. today announced a non-exclusive licensing agreement to research and develop Biosyn-patented microbicides for the prevention of HIV and other sexually transmitted diseases.

Although Antarctic krill (Euphausia superba) are one of the best-studied organisms of the open sea, key aspects of their life cycle have remained murky.