
A new technique allows researchers to culture colonies of mouse brain stem cells that can either propagate without differentiating or become normal brain cells at the flip of a genetic switch. (Conti, et al.)It's hard to grow stem cells in a dish. In particular, while it is possible to multiply mouse embryonic stem cells in culture, propagating stem cells that are specific to distinct tissues (e.g. neural stem cells) has proven to be a challenge. Neural stem cells are normally found in a specialized environment known as a neurosphere, which is thought to provide the necessary cellular signals to maintain populations of these undifferentiated cells.

