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NCI Scientists Visualize Gene Regulation in Living Cells

National Institutes of Health - Posted: May 22nd, 2008, 12:05pm EDT

A research team led by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), has applied advanced imaging methods and computer simulations to be able to glance at the regulation of a cancer-related gene in a living cell. They found that the efficiency with which the components of the cell’s gene reading machinery come together has an impact on gene expression, the process by which a gene translates its information into a new protein. The findings, published in the May 23, 2008 issue of "Molecular Cell", shed new light on the means by which living cells regulate gene activity.

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