Biology


Representative diverse origins of multicellularity are shown on a highly redacted and unrooted phylogenetic diagram of the major eukaryotic clades (modified from a variety of sources).
In the beginning there were single cells. Today, many millions of years later, most plants, animals, fungi, and algae are composed of multiple cells that work collaboratively as a single being. Despite the various ways these organisms achieved multicellularity, their conglomeration of cells operate cooperatively to consume energy, survive, and reproduce. But how did multicellularity evolve? Did it evolve once or multiple times? How did cells make the transition from life as a solo cell to associating and cooperating with other cells such that they work as a single, cohesive unit?

Biotechnology

A simple adjustment to a powerful gene-editing tool may be able to improve its specificity. In a report receiving advance online publication in Nature Biotechnology, Massachusetts General Hospital (MGH) investigators describe how adjusting the length of the the guide RNA (gRNA) component of the synthetic enzymes called CRISPR-Cas RNA-guided nucleases (RGNs) can substantially reduce the occurrence of DNA mutations at sites other than the intended target, a limitation the team had previously described just last year.

Molecular & Cell Biology


This is a 3D structure of Cryptochrome -- a blue light photoreceptor; a natural variation in a single amino acid shown in green, has impact on behavior and development of...
The circadian clock is a molecular network that generates daily rhythms, and is present in both plants and animals.




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