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Molecular & Cell Biology

Scientists have published results that will forever change the way researchers view the interplay between gene expression, DNA replication and the prevention of DNA damage.

Molecular & Cell Biology

Scientists at Harvard University are moving closer to answering some age-old questions.


A new finding from scientists at the National Institutes of Health could help efforts to design vaccines and other prevention tools to block HIV in the early stages of sexual transmission, before infection takes hold. Researchers at the NIH National Institute of Allergy and Infectious Diseases have helped explain genetic differences that can distinguish some early-transmitting HIVs—viruses found in an infected individual within the first month after infection—from forms of HIV isolated later in infection. These genetic features help HIV bind tightly to a molecule called integrin α4β7. According to the scientists, the capacity to bind tightly to α4β7 likely enhances the ability of certain HIV viruses to complete the many steps of sexual transmission and become the "founder" virus that establishes infection in an individual.


The Svalbard Global Seed Vault (SGSV) celebrated its third anniversary today with the arrival of seeds for rare lima beans, blight-resistant cantaloupe, and progenitors of antioxidant-rich red tomatoes from Peru and the Galapagos Islands. The arrival of these collections, including many drought- and flood-resistant varieties, comes at a time when natural and man-made risks to agriculture have reinforced the critical need to secure all the world's food crop varieties.