New research shows for the first time that molecules called microRNA can silence genes that protect the genome from cancer-causing mutations.

Using DNA samples and images from Earth-orbiting satellites, conservationists from Columbia University, the Wildlife Conservation Society, the American Museum of Natural History, and Fundación AquaMarina, are gathering new insights about the franciscana—a poorly known coastal dolphin species of eastern South America—in an effort to understand populations and conserve them.

Limited success in modelling the behaviour of the complex, unusual and unpredictable HIV virus has slowed efforts to develop an effective vaccine to prevent AIDS.

A series of novel imaging agents could light up tumors as they begin to form – before they turn deadly – and signal their transition to aggressive cancers.

Losses of managed honey bee colonies nationwide totaled 33.8 percent from all causes from October 2009 to April 2010, according to a survey conducted by the Apiary Inspectors of America (AIA) and the Agricultural Research Service (ARS). Beekeepers identified starvation, poor weather, and weak colonies going into winter as the top reasons for mortality in their operations.

Researchers at Centre for Ecological Research and Forestry Applications (CREAF, a Universitat Autònoma de Barcelona-affiliated centre) shed new light on the evolution of brain size in birds. Scientists have known for some time that migratory birds have smaller brains than their resident relatives. Now a new study looks into the reasons and concludes that the act of migrating leads to a reduced brain size. Authors point to the fact that the causes could be due to a need to reduce energetic, metabolic and cognitive costs. To reach these conclusions, scientists reconstructed the evolutionary history of one of the most numerous orders of birds, the passeriformes, a group which includes swallows, tits and crows.

A team of scientists led by the Department of Energy's Joint Genome Institute (JGI) and the University of California, Berkeley, is publishing this week the first genome sequence of an amphibian, the African clawed frog Xenopus tropicalis, filling in a major gap among the vertebrates sequenced to date.

ANAHEIM, CA – In studies on cancer, heart disease, neurological disorders and other degenerative conditions, some scientists are moving away from the "nature versus nurture" debate, and are finding you're not a creature of either genetics or environment, but both - with enormous implications for a new approach to health.

Whether different odors can be quickly distinguished depends on certain synapses in the brain that inhibit nerve stimulation. The researchers in Professor Dr. Thomas Kuner's team at the Institute of Anatomy and Cell Biology at Heidelberg University Medical School and Dr. Andreas Schäfer at the Max Planck Institute for Medical Research have shown that mice in which a certain receptor in the olfactory center is missing can distinguish similar smells more quickly than mice without genetic manipulation. This behavior was directly attributed to inhibitor loops between adjacent nerve cells.

Patients recovering from stroke sometimes behave as if completely unaware of one half of the world: colliding with obstacles on their left, eating food only from the right side of their plate, or failing to dress their left side. This puzzling phenomenon is termed "spatial neglect" and it affects roughly 45% of patients suffering from a stroke in the right side of the brain. The condition can indicate a long road to recovery, but researchers have now developed a quick and simple lottery game, which can be used to assess the extent of these symptoms and potentially aid the design of rehabilitation programmes. The findings are reported in the May 2010 issue of Elsevier's Cortex (http://www.elsevier.com/locate/cortex).

A University of Alberta-led research team has taken a major step forward in understanding how T cells are activated in the course of an immune response by combining nanotechnology and cell biology. T cells are the all important trigger that starts the human body's response to infection.

Just seeing someone who looks sick is enough to make your immune system work harder, according to a new study in which volunteers looked at pictures of sick people. This may help fight off pathogens, says Mark Schaller from the University of British Columbia who conducted the research. "It seems like it's probably good for the immune system to be responding especially aggressively at times when it looks like you are likely to be coming into contact with something that might make you sick."

Like all vertebrates, snakes, mice and humans have in common a skeleton made of segments, the vertebrae. But a snake has between 200-400 ribs extending from all vertebrae, from the neck to the tail-end, whereas mice have only 13 pairs of ribs, and humans have 12 pairs, in both cases making up the ribcage. In the latest issue of Developmental Cell(*), researchers from the Instituto Gulbenkian de Ciência, in Portugal, reveal that, contrary to what was thought, making ribs is not the default state for vertebrates, but is actually an active process of balancing the activities of a remarkable class of genes - the Hox genes.

A team led by scientists from the National Oceanography Centre in Southampton, have today set sail from Govan in Scotland towards the region of the North Atlantic Ocean affected by ash from the Icelandic volcano eruption to investigate potential impacts on ocean biology.

They are both nest-building social insects, but paper wasps and honey bees organize their colonies in very different ways. In a new study, researchers report that despite their differences, these insects rely on the same network of genes to guide their social behavior.

Scientists may be one step closer to being able to generate any type of cells and tissues from a patient's own cells. In a study that will appear in the journal Nature and is receiving early online release, investigators from the Massachusetts General Hospital Center for Regenerative Medicine (MGH-CRM) and the Harvard Stem Cell Institute (HSCI), describe finding that an important cluster of genes is inactivated in induced pluripotent stem cells (iPSCs) that do not have the full development potential of embryonic stem cells. Generated from adult cells, iPSCs have many characteristics of embryonic stem cells but also have had significant limitations.

Knocking genes out of action allows researchers to learn what genes do by seeing what goes wrong without them. University of Utah biologists pioneered the field. Mario Capecchi won a Nobel Prize for developing knockout mice. Kent Golic found a way to cripple fruit fly genes. Now, biologist Erik Jorgensen and colleagues have devised a procedure for knocking out genes in nematode worms.

Atomic force microscopy, a tactile-based probe technique, provides a three-dimensional nanoscale image of a material by gliding a needle-like arm across the material's surface. The core of AFM imaging workhorse is a cantilever with a sharp tip that deflects as it encounters undulations across a surface. Due to a minimum force required for imaging, conventional AFM cantilevers can deform or even tear apart living cells and other biological materials. While scientists have made strides in reducing this minimum force by making smaller cantilevers, the force is still too great to image cells with high resolution. Indeed, for imaging objects smaller than the diffraction limit of light—that is, nanometer dimensions—this approach hits a roadblock as the instrument can no longer sense minute forces.

Catalan researchers have discovered in the rubbish dump of Can Mata in the Vallès-Penedès basin (Catalonia) a new species of Pliopithecus primate, considered an extinct family of primitive Catarrhini primates (or "Old World monkeys"). The fragments of jaw and molars found in this large site demonstrate that Pliopithecus canmatensis belongs to this group, which includes the first Catarrhini that dispersed from Africa to Eurasia.

A new study from the Journal of Marital & Family Therapy warns of the dramatic rise in the use of psychotropic medications for children. One in every fifty Americans is now considered permanently disabled by mental illness, and up to eight million children take one or more psychotropic drugs.

Researchers have discovered 2,363 new DNA sequences corresponding to 730 regions on the human genome by using new approaches. These sequences represent segments of the genome that were not charted in the reference map of the human genome.

Their numbers continue to expand. They are spreading throughout the Caribbean Sea. Eradication appears almost impossible. Even limited amounts of control will be extremely difficult, and right now the best available plan is to capture and eat them.

The fifth Howler Monkey census at the Smithsonian's Barro Colorado Island research station in Panama, organized by Katie Milton, professor in the department of Environmental Science, Policy & Management at the University of California, Berkeley, revealed that monkey numbers have not changed significantly since the first census 33 years ago.

Scientists investigating ovale malaria, a form of the disease thought to be caused by a single species of parasite, have confirmed that the parasite is actually two similar but distinct species which do not reproduce with each other, according to research published in The Journal of Infectious Diseases.

Showcasing its energy research initiatives for an Earth Day event on April 22 at the Pentagon, the Office of Naval Research (ONR) will highlight the microbial fuel cell, a device that could revolutionize naval energy use by converting decomposed marine organisms into electricity.

Ocean explorers are puzzling out Nature's purpose behind an astonishing variety of tiny ocean creatures like microbes and zooplankton animals - each perhaps a ticket-holder in life's lottery, awaiting conditions that will allow it to prosper and dominate.

Scientists have developed a brain implant that essentially melts into place, snugly fitting to the brain's surface. The technology could pave the way for better devices to monitor and control seizures, and to transmit signals from the brain past damaged parts of the spinal cord.

In a multidisciplinary approach, Professor Yves Barral, from the Biology Department at ETH Zurich and the computer scientists Dr. Gina Cannarozzi and Professor Gaston Gonnet, from the Computer Science Department of ETH Zurich and the SIB Swiss Institute of Bioinformatics, joined forces to chase possible sub-codes in genomic information. The study, which will be published in today's issue of the journal Cell, led to the identification of novel sequence biases and their role in the control of genomic expression.

A natural product found in both coconut oil and human breast milk – lauric acid -- shines as a possible new acne treatment thanks to a bioengineering graduate student from the UC San Diego Jacobs School of Engineering. The student developed a "smart delivery system" – published in the journal ACS Nano in March – capable of delivering lauric-acid-filled nano-scale bombs directly to skin-dwelling bacteria (Propionibacterium acnes) that cause common acne.

Using a method they developed to watch moment to moment as they move a molecule to precise sites inside live human cells, Johns Hopkins scientists are closer to understanding why and how a protein at one location may signal division and growth, and the same protein at another location, death.

Using powerful DNA sequencing technology to decode the genomes of cancer patients, scientists at Washington University School of Medicine in St. Louis are getting an unprecedented look at the genetic basis of a highly lethal breast cancer that disproportionately affects younger women and those who are African-American.

BOSTON, Mass. (April 14, 2010) — How does the brain work? This question is one of the greatest scientific mysteries, and neurobiologists have only recently begun to piece together the molecular building blocks that enable human beings to be "thinking" animals.

Scientists in Alaska have discovered that lingering oil from the 1989 Exxon Valdez spill is still being ingested by some wildlife more than 20 years after the disaster. The research, published in Environmental Toxicology and Chemistry, uses biomarkers to reveal long-term exposure to oil in harlequin ducks and demonstrates how consequences of oil spills are measured in decades rather than years.

In an electrifying first, Stanford scientists have plugged in to algae cells and harnessed a tiny electric current. They found it at the very source of energy production – photosynthesis, a plant's method of converting sunlight to chemical energy. It may be a first step toward generating "high efficiency" bioelectricity that doesn't give off carbon dioxide as a byproduct, the researchers say.

Whether forests are dying back, or just drying out, projections for warming show the Pacific Northwest is becoming primed for more wildfires.

From deep within the genomes of organisms as diverse as plants, worms and yeast, scientists have uncovered new genes responsible for causing human diseases such as cancer and deafness.

Scientists at the University of Liverpool have discovered that dangerous strains of Salmonella are beginning to emerge in people infected with HIV in Africa.

Researchers at Uppsala University have developed a new method for identifying genetic variation, including mutations, in active genes. Hopes are strong that the method represents an important research tool that will lead to the development of new diagnostic tests.

Using a sensor that weighs cells with unprecedented precision, MIT and Harvard researchers have measured the rate at which single cells accumulate mass — a feat that could shed light on how cells control their growth and why those controls fail in cancer cells.

Chapel Hill, NC – Scientists have shown in multiple contexts that DNA damage over our lifetimes is a key mechanism behind the development of cancer and other age-related diseases. Not everyone gets these diseases, because the body has multiple mechanisms for repairing the damage caused to DNA by aging, the environment and other human behaviors – but the mechanisms behind certain kinds of DNA repair have not been well-understood.