Biology

Each cusp of our teeth is regulated by genes which carefully control the development. A similar genetic puzzle also regulates the differentiation of our other organs and of all living organisms. A team of researchers at the Institute of Biotechnology of the University of Helsinki has developed a computer model reproducing population-level variation in complex structures like teeth and organs. The research takes a step towards the growing of correctly shaped teeth and other organs. The results were published last week in Nature, the esteemed science journal.

Biotechnology

The film "Avatar" isn't the only 3-D blockbuster making a splash this winter. A team of scientists from Houston's Texas Medical Center this week unveiled a new technique for growing 3-D cell cultures, a technological leap from the flat petri dish that could save millions of dollars in drug-testing costs. The research is reported in Nature Nanotechnology.

Molecular & Cell Biology

Researchers at the Department of Chemistry at the Technische Universität München (TUM) have developed a method that allows the observation of local movements in proteins on a time scale of nanoseconds to microseconds. Upon examining movements of the protein villin using this method they found two structures that were otherwise barely distinguishable from one another. Quick nanosecond-scale structure changes essential for the protein function can take place in the one, while the other remains rigid. These results have been published in the online issue of the journal "Proceedings of the National Academy of Sciences, USA" (PNAS).

Bioinformatics

UC Irvine researchers have played a leading role in the genome sequencing of Hydra, a freshwater polyp that has been a staple of biological research for 300 years.

Biology

An international team led by scientists at the Sainsbury Laboratory in Norwich,UK, have transferred broad spectrum resistance against some important plant diseases across different plant families. This breakthrough provides a new way to produce crops with sustainable resistance to economically important diseases.

Biology

Researchers at the University of Calgary have discovered the unique genes that allow the opium poppy to make codeine and morphine, thus opening doors to alternate methods of producing these effective painkillers either by manufacturing them in a lab or controlling the production of these compounds in the plant.

Molecular & Cell Biology

Using a novel light activation technique, Scripps Research Institute scientists have been able to turn molecules with only a modest ability to fight specific proteins into virtual protein destroyers.




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