Scientists have discovered a molecular pathway that works through the immune system to regenerate damaged kidney tissues and may lead to new therapies for repairing injury in a number of organs systems.

A new study from the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa suggests that stem cells intentionally break their own DNA as a way of regulating tissue development. The study, published in Proceedings of the National Academy of Science (PNAS), could dramatically change how researchers think about tissue development, stem cells and cancer.

'Free-stall', untied cattle in small herds produce less milk than cows tied to their stalls but have a higher reproductive performance and suffer less teat injuries and metabolic diseases. Researchers writing in BioMed Central's open access journal Acta Veterinaria Scandinavica compared performance and health within the two stall types in response to a ban on the construction of new tie-stalls.

A new international study reported in PLoS Medicine confirms that a single dose of nevirapine (sdNVP) can lead to HIV treatment failure in women who receive the drug to prevent transmission of the AIDS virus to their infants. However, the increased risk of failure could only be detected in women who began full HIV treatment within about a year after receiving sdNVP.