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Category: Biology

Recurrent DSB clusters in neural stem/progenitor cells are shown.
The genome of developing brain cells harbors 27 clusters or hotspots where its DNA is much more likely to break in some places than others, researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital, Harvard Medical School, and the Howard Hughes Medical Institute report in the journal Cell. Those hotspots appear in genes associated with brain tumors and a number of neurodevelopmental and neuropsychiatric conditions, raising new questions about these conditions' origins, as well as how the brain generates a diversity of circuitry during development.

Full articleFebruary 11, 2016 05:06 PM306 views
Category: Environment

A major coral bleaching event took place on this part of the Great Barrier Reef in Australia.
A study at Oregon State University has concluded that significant outbreaks of viruses may be associated with coral bleaching events, especially as a result of multiple environmental stresses.

Full articleFebruary 11, 2016 05:06 PM315 views
Category: Molecular & Cell Biology

Graphic of microtubules, the 'railway network' within every cell of the human body
Researchers from the University of Warwick have discovered how cells in the human body build their own 'railway networks', throwing light on how diseases such as bowel cancer work. The results have just been published in Nature Scientific Reports.

Full articleFebruary 11, 2016 05:06 PM256 views
Category: Molecular & Cell Biology

A new imaging technique has allowed researchers at North Carolina State University, the University of North Carolina at Chapel Hill, and the University of Pittsburgh to see how DNA loops around a protein that aids in the formation of a special structure in telomeres. The work provides new insights into the structure of telomeres and how they are maintained.

Full articleFebruary 11, 2016 05:06 PM213 views
Category: Molecular & Cell Biology

If you're fat, can you blame it on your genes? The answer is a qualified yes. Maybe. Under certain circumstances. Researchers are moving towards a better understanding of some of the roots of obesity.

Full articleFebruary 9, 2016 07:45 PM1083 views
Category: Environment

Historical and modern photographs of Stone Island taken in a) 1915 (photographer unknown); b) 1994 (photographer A. Elliot © Commonwealth of Australia GBRMPA); c) 2012 (photographer H. Markham); and Bramston Reef taken in d) c.1890 (W. Saville-Kent); e) 1994 (photographer A. Elliot © Commonwealth of Australia GBRMPA); f) 2012 (photographer T. Clark). Landscape features in the background of the images helped to locate the same sites: Gloucester Island (GI) and Cape Gloucester (CG).

Source: Clark et al. 2016. The timing of significant Great Barrier Reef coral loss captured by a series of historical photos has been accurately determined for the first time by a University of Queensland)-led study.

Full articleFebruary 9, 2016 07:45 PM760 views
Category: Bioinformatics

Researchers sequence the genome of the Lyme-disease-causing tick and find lots of duplicative elements.
Researchers have sequenced the genetic blueprint of one of the most prolific pathogen-transmitting agents on the planet - the Lyme-disease-spreading tick (Ixodes scapularis) that bites humans. The findings could lead to advances in not only disrupting the tick's capacity to spread diseases but also in eradicating the pest.

Full articleFebruary 9, 2016 07:45 PM869 views
Category: Biology

Biologists have found genetic mechanisms that let the Atlantic molly live in toxic, acidic water.
A Washington State University biologist has found the genetic mechanisms that lets a fish live in toxic, acidic water. The discovery opens the door to new insights into the functioning of other "extremophiles" and how they adapt to their challenging environments.

Full articleFebruary 9, 2016 07:45 PM914 views
Category: Bioinformatics

Database searches for DNA sequences that can take biologists and medical researchers days can now be completed in a matter of minutes, thanks to a new search method developed by computer scientists at Carnegie Mellon University.

Full articleFebruary 8, 2016 04:12 PM1186 views
Category: Health & Medicine

A research team led by St. Jude Children's Research Hospital scientists has discovered details of how the abnormal breakage and rearrangement of chromosomes in white blood cells triggers a particularly aggressive form of acute lymphoblastic leukemia (ALL). Such leukemias are cancers of white blood cells, in which genetic mutations trigger overproduction of immature cells, called lymphoblasts.

Full articleFebruary 8, 2016 04:12 PM1001 views
Category: Health & Medicine

A concise "Five things to know about.... Zika virus infection" article for physicians highlights key points about this newly emerged virus in CMAJ (Canadian Medical Association Journal)

Full articleFebruary 8, 2016 04:12 PM1085 views
Category: AIDS & HIV

New research findings published in the February 2016 issue of the Journal of Leukocyte Biology, suggest that a new therapeutic strategy for HIV may already be available by repurposing an existing prescription drug. The drug, an enzyme called adenosine deaminase, or ADA, ultimately may be able to activate the immune system against HIV and to help the immune system "remember" the virus to prevent or quickly eliminate future infection.

Full articleFebruary 2, 2016 04:38 PM4028 views
Category: Biotechnology

Researchers from the General Physics Institute of the Russian Academy of Sciences (GPI RAS) and Moscow Institute of Physics and Technology (MIPT) have developed a new biosensor test system based on magnetic nanoparticles. It is designed to provide highly accurate measurements of the concentration of protein molecules (e.g. markers, which indicate the onset or development of a disease) in various samples, including opaque solutions or strongly coloured liquids.

Full articleFebruary 2, 2016 04:38 PM1788 views
Category: Molecular & Cell Biology

Supposed "junk" DNA, found in between genes, plays a role in suppressing cancer, according to new research by Universities of Bath and Cambridge. The human genome contains around three metres of DNA, of which only about two per cent contains genes that code for proteins. Since the sequencing of the complete human genome in 2000, scientists have puzzled over the role of the remaining 98 per cent.

Full articleFebruary 2, 2016 04:38 PM2247 views

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